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一名患有间歇性胸痛的年轻成年人的Wellens综合征病例:了解独特模式及临床关联

A Case of Wellens Syndrome in a Young Adult With Intermittent Chest Pain: Understanding the Unique Pattern and Clinical Correlation.

作者信息

Tolu-Akinnawo Oluwaremilekun, Dufera Rabira R, Akamah Joseph

机构信息

Internal Medicine, Meharry Medical College, Nashville, USA.

Cardiology, Nashville General Hospital, Nashville, USA.

出版信息

Cureus. 2023 Mar 28;15(3):e36820. doi: 10.7759/cureus.36820. eCollection 2023 Mar.

DOI:10.7759/cureus.36820
PMID:37123742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10139730/
Abstract

Wellens syndrome is a unique electrocardiographic (ECG) pattern usually suggestive of critical stenosis of the left anterior descending (LAD) coronary artery. Providers must recognize this pattern as it frequently occurs in symptom-free periods and represents a pre-infarction stage requiring early intervention. We present the case of a 39-year-old male with a past medical history of hypertension who was brought to the emergency department due to complaints of worsening recurrent intermittent squeezing left-sided chest pain of two months duration. Cardiac enzymes were within limits. ECG done at triage was significant for biphasic T waves in leads V2-V5 consistent with type A Wellens syndrome. The cardiology team consulted, with the patient subsequently having a percutaneous coronary intervention to the mid and proximal portion of the LAD. The patient was later discharged on the third day of admission on guideline-directed medical therapy, with plans to follow up closely with the cardiology clinic. This case highlights the significance of using the characteristics pattern of Wellens syndrome in providing critical diagnostic and prognostic value. This article aimed to promote awareness of Wellens syndrome, the clinical correlation, and the role of timely acute management.

摘要

Wellens综合征是一种独特的心电图(ECG)模式,通常提示左前降支(LAD)冠状动脉严重狭窄。医护人员必须认识到这种模式,因为它经常出现在无症状期,代表着需要早期干预的梗死前期。我们报告一例39岁男性病例,该患者有高血压病史,因反复出现持续两个月的左侧胸部间歇性压榨性疼痛加重而被送往急诊科。心肌酶在正常范围内。分诊时进行的心电图显示,V2-V5导联出现双相T波,符合A型Wellens综合征。心内科团队会诊后,患者随后接受了LAD中、近端的经皮冠状动脉介入治疗。患者在入院第三天在指南指导下接受药物治疗后出院,并计划在心内科门诊密切随访。该病例强调了利用Wellens综合征的特征性模式提供关键诊断和预后价值的重要性。本文旨在提高对Wellens综合征、临床相关性以及及时急性处理作用的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/d00e7c896b06/cureus-0015-00000036820-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/0818748218a2/cureus-0015-00000036820-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/abd8a02b2c73/cureus-0015-00000036820-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/d00e7c896b06/cureus-0015-00000036820-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/0818748218a2/cureus-0015-00000036820-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/abd8a02b2c73/cureus-0015-00000036820-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f456/10139730/d00e7c896b06/cureus-0015-00000036820-i03.jpg

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本文引用的文献

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A Rare Presentation of a Rare Entity: Wellens Syndrome with Subtle Terminal Wave Changes.一种罕见疾病的罕见表现:伴有细微终末波改变的Wellens综合征。
Case Rep Emerg Med. 2019 Sep 16;2019:1582030. doi: 10.1155/2019/1582030. eCollection 2019.
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Wellens' syndrome: a life-saving diagnosis.Wellens综合征:一种能挽救生命的诊断。
Cardiovasc J Afr. 2019;30(4):e1-e3. doi: 10.5830/CVJA-2019-010. Epub 2019 May 24.
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Atypical electrocardiographic manifestations of ischemia: a case of dynamic Wellens patterns.缺血性非典型心电图表现:一例动态Wellens综合征病例
J Geriatr Cardiol. 2018 Nov;15(11):710-712. doi: 10.11909/j.issn.1671-5411.2018.11.006.
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Pseudo-Wellens' syndrome secondary to concurrent cannabis and phencyclidine intoxication.并发大麻和苯环己哌啶中毒继发的假性威伦综合征
BMJ Case Rep. 2018 Jun 29;2018:bcr-2018-225755. doi: 10.1136/bcr-2018-225755.
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Newer perspectives of coronary artery disease in young.年轻人冠状动脉疾病的新观点
World J Cardiol. 2016 Dec 26;8(12):728-734. doi: 10.4330/wjc.v8.i12.728.
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Omnious T-wave inversions: Wellens' syndrome revisited.不祥的T波倒置:重温Wellens综合征。
J Community Hosp Intern Med Perspect. 2016 Sep 7;6(4):32011. doi: 10.3402/jchimp.v6.32011. eCollection 2016.
8
Wellens syndrome, a predictor of critical left anterior descending artery stenosis.Wellens综合征,左前降支严重狭窄的预测指标。
Postgrad Med J. 2017 Jan;93(1095):53. doi: 10.1136/postgradmedj-2016-134260. Epub 2016 Jul 5.
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