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急性冠状动脉综合征的非典型表现及Wellens综合征的重要性。

Atypical Presentation of Acute Coronary Syndrome and Importance of Wellens' Syndrome.

作者信息

Kyaw Kyaw, Latt Htun, Aung Sammy San Myint, Tun Nay Min, Phoo Wut-Yi, Yin Htwe Htwe

机构信息

Institute for Heart and Vascular Health, Renown Regional Medical Center, Reno, NV, USA.

Department of Internal Medicine, University of Nevada-Reno, School of Medicine, Reno, NV, USA.

出版信息

Am J Case Rep. 2018 Feb 22;19:199-202. doi: 10.12659/ajcr.907992.

DOI:10.12659/ajcr.907992
PMID:29467360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5829624/
Abstract

BACKGROUND Acute coronary syndrome (ACS) is a common and potentially life-threatening condition encountered in emergency departments. Despite its dreaded nature, nearly one-third of ACS present without chest pain and may mislead clinicians. Additionally, Wellens' syndrome is a pre-infarction stage of significant proximal left anterior descending (LAD) artery stenosis, which can lead to extensive anterior wall myocardial infarction without timely intervention.  CASE REPORT We report the case of a 74-year-old woman presenting with isolated throat pain and Wellens' pattern in the initial EKG, which prompted the proper workup and management. Subsequently, coronary angiogram revealed more than 90% occlusion of the proximal LAD artery, and a drug-eluting stent was deployed. The patient did well after the procedure and the follow-up at 2 weeks after discharge was uneventful.   CONCLUSIONS This case highlights the importance of awareness of atypical presentation of ACS and importance of Wellens' syndrome. We also discuss the incidence of craniofacial symptoms of ACS, and the epidemiology, pathophysiology, management, and prognosis of Wellens' syndrome.

摘要

背景 急性冠状动脉综合征(ACS)是急诊科常见的、可能危及生命的病症。尽管其性质可怕,但近三分之一的ACS患者并无胸痛症状,这可能会误导临床医生。此外,Wellens综合征是左前降支(LAD)近端严重狭窄的梗死前期,若不及时干预,可导致大面积前壁心肌梗死。 病例报告 我们报告一例74岁女性患者,最初心电图显示仅有咽痛及Wellens图形,这促使进行了恰当的检查和治疗。随后,冠状动脉造影显示LAD近端闭塞超过90%,遂植入药物洗脱支架。术后患者情况良好,出院后2周随访无异常。 结论 本病例突出了认识ACS非典型表现及Wellens综合征的重要性。我们还讨论了ACS颅面部症状的发生率以及Wellens综合征的流行病学、病理生理学、治疗及预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/2dba681c0e6b/amjcaserep-19-199-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/cf150cc94022/amjcaserep-19-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/5fa695288f46/amjcaserep-19-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/2dba681c0e6b/amjcaserep-19-199-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/cf150cc94022/amjcaserep-19-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/5fa695288f46/amjcaserep-19-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25c/5829624/2dba681c0e6b/amjcaserep-19-199-g003.jpg

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2
ST-Elevation Myocardial Infarction Due to Left Anterior Descending Artery Occlusion Presenting Primarily with Otalgia.主要表现为耳痛的左前降支动脉闭塞所致ST段抬高型心肌梗死
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T-wave changes in patients with Wellens syndrome are associated with increased myocardial mechanical and electrical dispersion.
Cureus. 2022 Jul 16;14(7):e26920. doi: 10.7759/cureus.26920. eCollection 2022 Jul.
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Electrocardiographic findings of Wellens syndrome due to coronary artery-pulmonary artery fistula.因冠状动脉-肺动脉瘘导致的 Wellens 综合征的心电图表现。
J Int Med Res. 2020 May;48(5):300060520911495. doi: 10.1177/0300060520911495.
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Wellens' Syndrome Presenting as Epigastric Pain and Syncope: An Unusual Presentation.以腹痛和晕厥为表现的Wellens综合征:一种不寻常的表现。
Cureus. 2020 Feb 4;12(2):e6877. doi: 10.7759/cureus.6877.
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Pseudo-Wellens' syndrome secondary to concurrent cannabis and phencyclidine intoxication.并发大麻和苯环己哌啶中毒继发的假性威伦综合征
BMJ Case Rep. 2018 Jun 29;2018:bcr-2018-225755. doi: 10.1136/bcr-2018-225755.
Wellens综合征患者的T波改变与心肌机械和电离散增加有关。
Int J Cardiovasc Imaging. 2017 Oct;33(10):1541-1549. doi: 10.1007/s10554-017-1181-4. Epub 2017 May 27.
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