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薄壁囊性肺癌:45例病例研究

Thin-wall cystic lung cancer: A study of 45 cases.

作者信息

Deng Hui, Zhang Jingyuan, Zhao Sheng, Zhang Jie, Jiang Hong, Chen Xiaolan, Wang Dongxu, Gao Jie, Wu Chongchogn, Pan Lei, Wang Yong, Xue Xinying

机构信息

Department of Special Medical Treatment-Respiratory Disease, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. China.

Department of Cardiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. China.

出版信息

Oncol Lett. 2018 Jul;16(1):755-760. doi: 10.3892/ol.2018.8707. Epub 2018 May 14.

Abstract

Thin-wall cystic lung cancer is uncommon. Consequently, there is a lack of knowledge concerning the features of this type of lung cancer, which may lead to misdiagnosis and delayed treatment. The aim of the present study is to understand the invasiveness and metastasis of thin-wall cystic lung cancer. The prognosis of this type of cancer will also be discussed. The present study attempted to determine the pathological interpretation of the imaging results. A total of 45 patients with this specific type of lung cancer were analyzed retrospectively based on the review of medical records, radiological findings, pathological changes and treatment strategies. Certain patients were also telephoned in order to learn about their recent physical conditions. Thin-wall cystic lung cancer displayed suspected malignant signs. The majority of these cases are adenocarcinoma, but certain cases of squamous cell carcinoma may also display cysts on their images. Although thin-wall cystic lung cancer is often thought to progress slowly, certain cases may progress rapidly. Distant metastasis, which is relatively rare, occurred in three cases. Cancer cells proliferate along the terminal bronchioles and destroy the lung tissues exposing the bronchial arteries and adjacent bronchi. Therefore, separation in cysts on the images was observed. In the majority of cases, the thin-wall cystic lung cancer proliferates slowly, but in a few cases it may be very aggressive.

摘要

薄壁囊性肺癌并不常见。因此,人们对这类肺癌的特征缺乏了解,这可能导致误诊和治疗延误。本研究的目的是了解薄壁囊性肺癌的侵袭性和转移情况。还将讨论这类癌症的预后。本研究试图确定影像学结果的病理学解释。通过回顾病历、影像学检查结果、病理变化和治疗策略,对45例患有这种特定类型肺癌的患者进行了回顾性分析。还对部分患者进行了电话随访,以了解他们近期的身体状况。薄壁囊性肺癌表现出可疑的恶性征象。这些病例大多数为腺癌,但某些鳞状细胞癌病例在影像学上也可能显示囊肿。尽管薄壁囊性肺癌通常被认为进展缓慢,但某些病例可能进展迅速。有3例发生了相对少见的远处转移。癌细胞沿终末细支气管增殖,破坏肺组织,暴露支气管动脉和相邻支气管。因此,在影像学上观察到囊肿内有分隔。在大多数情况下,薄壁囊性肺癌增殖缓慢,但少数情况下可能具有很强的侵袭性。

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