肺动脉高压：肺移植的作用。

Pulmonary Hypertension: The Role of Lung Transplantation.

机构信息

Lung Institute, University of Arizona, Banner University Medical Center, 755 E. McDowell Road, 3rd Floor, Phoenix, AZ 85006, USA.

Department of Respiratory Disease, Federico II University of Naples, Naples, Italy.

出版信息

Heart Fail Clin. 2018 Jul;14(3):327-331. doi: 10.1016/j.hfc.2018.02.007.

DOI:10.1016/j.hfc.2018.02.007

PMID:29966630

Abstract

Despite advances in targeted medical therapy, pulmonary arterial hypertension (PAH) remains a fatal disease because of progressive right ventricular dysfunction. For patients who are refractory to medical therapy, heart-lung and lung transplantation are important treatment options. Because of longer waiting time, surgical interventions including extracorporeal lung support and atrial septostomy can be used in PAH patients bridging to transplantation.

摘要

尽管在靶向医学治疗方面取得了进展，但肺动脉高压（PAH）仍然是一种致命的疾病，因为它会导致右心室功能进行性下降。对于对药物治疗无反应的患者，心肺和肺移植是重要的治疗选择。由于等待时间较长，体外肺支持和房间隔造口术等手术干预措施可用于 PAH 患者桥接移植。