Barthó L, Pethö G, Rónai Z
Br J Pharmacol. 1985 Oct;86(2):315-7. doi: 10.1111/j.1476-5381.1985.tb08898.x.
Atropine-resistant longitudinal contractions of the guinea-pig ileum due to field stimulation were greatly augmented by theophylline (150 microM). Adenosine exerted an opposite effect. Theophylline did not potentiate contractions evoked by exogenous substance P. It is suggested that a theophylline-sensitive inhibitory mechanism (possibly mediated by adenosine or a related substance) controls transmitter release from enteric non-cholinergic excitatory neurones.
由电场刺激引起的豚鼠回肠对阿托品耐药的纵向收缩，可被茶碱（150微摩尔）极大增强。腺苷则产生相反的作用。茶碱不能增强外源性P物质诱发的收缩。提示茶碱敏感的抑制机制（可能由腺苷或相关物质介导）控制着肠道非胆碱能兴奋性神经元的递质释放。
