母体 Zika 病毒感染导致的非人灵长类动物流产和死胎。
Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.
机构信息
Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
California National Primate Research Center, University of California-Davis, Davis, CA, USA.
出版信息
Nat Med. 2018 Aug;24(8):1104-1107. doi: 10.1038/s41591-018-0088-5. Epub 2018 Jul 2.
Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few clinical signs of infection. Pregnancy loss due to asymptomatic ZIKV infection may therefore be a common but under-recognized adverse outcome related to maternal ZIKV infection.
寨卡病毒（ZIKV）感染与先天性缺陷和妊娠丢失有关。在这里，我们发现，26%的在妊娠早期感染亚洲/美洲 ZIKV 的非人类灵长类动物尽管表现出很少的感染临床症状，但在妊娠后期仍经历胎儿死亡。因此，无症状 ZIKV 感染引起的妊娠丢失可能是一种常见但未被认识到的与母体 ZIKV 感染相关的不良后果。
Zotero 插件