Lee Eun Joo, Lee Hae Sang, Park Jun Eun, Hwang Jin Soon
Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.
Ann Pediatr Endocrinol Metab. 2018 Jun;23(2):99-102. doi: 10.6065/apem.2018.23.2.99. Epub 2018 Jun 20.
Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease characterized by fever and lymphadenopathy. The etiology of KFD is unknown, but an autoimmune cause has been suggested. Hashimoto thyroiditis is the most common autoimmune thyroid disorder in children and is known to be associated with other autoimmune diseases. Only a few cases of Hashimoto thyroiditis associated with KFD have been documented. We report a case of a 16-year-old girl who was first diagnosed with KFD and developed Hashimoto thyroiditis 2 years and 6 months later during her follow-up period. Physicians of patients with KFD should consider the possibility of autoimmune diseases like Hashimoto's thyroiditis.
菊池-藤本病(KFD)是一种以发热和淋巴结病为特征的良性自限性疾病。KFD的病因尚不清楚,但有人提出是自身免疫性病因。桥本甲状腺炎是儿童中最常见的自身免疫性甲状腺疾病,并且已知与其他自身免疫性疾病有关。仅有少数桥本甲状腺炎合并KFD的病例有文献记载。我们报告一例16岁女孩,最初被诊断为KFD,在随访期间2年零6个月后发生了桥本甲状腺炎。KFD患者的医生应考虑自身免疫性疾病如桥本甲状腺炎的可能性。