Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Nutrients. 2018 Jul 3;10(7):859. doi: 10.3390/nu10070859.
Metabolic syndrome (MetS) is a common global health problem. This study aims to assess nutrient intake and risk of MetS in middle-aged Koreans based in residential areas. Participants were 161,326 (142,137 in urban and 19,189 in rural) subjects enrolled in the Korea Genome and Epidemiology Study. The prevalence of MetS was much higher in rural (39.8%) than that in urban (22.5%) subjects ( < 0.001). The rural residents showed significantly higher blood pressure ( < 0.001), serum triglyceride levels ( < 0.001), and LDL (Low density lipoprotein)-cholesterol level ( < 0.001), as well as the odds ratio (OR) for MetS (OR = 1.65, 95% CI: 1.59⁻1.71), compared to urban residents. The rural subjects showed a higher consumption of carbohydrate and sodium compared to the urban subjects ( < 0.001). After adjusting for potential confounders, subjects in the highest quartile of carbohydrate intake had higher OR for MetS (OR = 1.23, 95% CI: 1.15⁻1.32) and those in the highest quartile of sodium intake had a higher chance of having MetS (OR = 1.11, 95% CI: 1.07⁻1.16) than did those in the lowest quartiles. Our results suggested that the higher consumption of carbohydrate and sodium in rural residents might be associated with the increased risk of MetS in this population.
代谢综合征（MetS）是一个常见的全球健康问题。本研究旨在评估居住在社区的中年韩国人的营养摄入与 MetS 风险。参与者为 161326 人（城市 142137 人，农村 19189 人），他们均来自韩国基因与流行病学研究。农村居民（39.8%）的 MetS 患病率明显高于城市居民（22.5%）（<0.001）。与城市居民相比，农村居民的血压（<0.001）、血清甘油三酯水平（<0.001）和 LDL（低密度脂蛋白）-胆固醇水平（<0.001）更高，MetS 的比值比（OR）也更高（OR=1.65，95%CI：1.59-1.71）。与城市居民相比，农村居民的碳水化合物和钠摄入量更高（<0.001）。在调整了潜在混杂因素后，碳水化合物摄入量最高四分位数的受试者患 MetS 的比值比（OR=1.23，95%CI：1.15-1.32）更高，钠摄入量最高四分位数的受试者患 MetS 的可能性更高（OR=1.11，95%CI：1.07-1.16）。我们的结果表明，农村居民碳水化合物和钠摄入量较高可能与该人群 MetS 风险增加有关。
