Hong Jee Yeon, Kim Yu-Mi, Shin Min-Ho, Koh Sang-Baek, Kim Hyeon Chang, Kim Mi Kyung
Department of Preventive Medicine, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Institute for Health and Society, Hanyang University, Seoul, Republic of Korea.
Br J Nutr. 2025 Jul 28;134(2):147-155. doi: 10.1017/S0007114525103905. Epub 2025 Jul 14.
Metabolic syndrome (MetS) is associated with an increased risk of CVD, type 2 diabetes and death from all causes. Dietary factors correlate with MetS, making diet a potential target for intervention. We used data from the 2012–2016 Korea National Health and Nutrition Examination Survey (KNHANES, 12 122) to identify a dietary pattern (DP) using thirty-nine predefined food groups as predictors. MetS components were used as the response variable with the food groups in reduced rank regression followed by stepwise linear regression analyses. We then verified the Korean status of the DP externally in the Cardiovascular Disease Association Study (CAVAS) ( 8277) and the Health EXAminees (HEXA) study ( 48 610). The DP score, which included twenty food groups, showed significant positive associations with all MetS components and a higher prevalence ratio in KNHANES participants ( < 0·0001). Although the score was NS in CAVAS ( = 0·0913), it showed a strong positive association with MetS prevalence in HEXA ( < 0·0001). We identified and tested a DP associated with MetS in Korean populations. This DP may be a useful tool for assessing MetS risk. Although the score was linked to higher MetS risk, particularly in the predominantly urban population of the HEXA study, further validation in more diverse populations is needed.
代谢综合征（MetS）与心血管疾病（CVD）、2型糖尿病及全因死亡风险增加相关。饮食因素与代谢综合征相关，使得饮食成为一个潜在的干预靶点。我们使用2012 - 2016年韩国国家健康与营养检查调查（KNHANES，共12122人）的数据，以39个预先定义的食物组作为预测指标来确定一种饮食模式（DP）。在降秩回归后，将代谢综合征的组成部分用作响应变量，食物组用作自变量，随后进行逐步线性回归分析。然后，我们在心血管疾病关联研究（CAVAS，共8277人）和健康体检者（HEXA）研究（共48610人）中对外验证了该饮食模式在韩国人群中的情况。包含20个食物组的饮食模式得分与所有代谢综合征组成部分均呈显著正相关，且在KNHANES参与者中的患病率更高（<0.0001）。尽管该得分在CAVAS研究中无统计学意义（=0.0913），但在HEXA研究中与代谢综合征患病率呈强正相关（<0.0001）。我们在韩国人群中识别并测试了一种与代谢综合征相关的饮食模式。这种饮食模式可能是评估代谢综合征风险的有用工具。尽管该得分与更高的代谢综合征风险相关，尤其是在HEXA研究中以城市人口为主的人群中，但仍需要在更多样化的人群中进行进一步验证。
