Ribeiro Cristiane Crisp Martins, Shimo Antonieta Keiko Kakuda, Lopes Maria Helena Baena de Moraes, Lamas José Luiz Tatagiba
Universidade Estadual de Campinas, School of Nursing. Campinas, São Paulo, Brazil.
Rev Bras Enferm. 2018;71(suppl 3):1453-1459. doi: 10.1590/0034-7167-2017-0317.
To identify evidence in the literature of the relationship between the use of different hormonal contraceptive methods and alterations in women's blood pressure values.
This is an integrative literature review, consisting of ten scientific articles published in PubMed and BVS, between 2012 and 2016, selected by keywords, available fully and free of charge, in English, Portuguese, or Spanish.
The articles showed that exogenous estrogen helps in the activation of the renin-angiotensin-aldosterone system causing hypertensive effects even in small doses; and that combined use with drospirenone reduces these effects. Routes of administration without passage through the liver and use of isolated progestin showed promising results in reducing the effects on blood pressure.
There is evidence in the literature of pressure alterations associated with different hormonal contraceptives and that personal history of morbidities are to be considered in an attempt to reduce the effects on the cardiovascular system.
确定文献中关于不同激素避孕方法的使用与女性血压值变化之间关系的证据。
这是一篇综合性文献综述，由2012年至2016年间发表在PubMed和BVS上的十篇科学文章组成，通过关键词进行筛选，文章可免费获取全文，语言为英语、葡萄牙语或西班牙语。
文章表明，外源性雌激素即使小剂量也有助于激活肾素 - 血管紧张素 - 醛固酮系统，从而产生高血压效应；与屈螺酮联合使用可降低这些效应。不经肝脏的给药途径以及单独使用孕激素在降低对血压的影响方面显示出有前景的结果。
文献中有证据表明不同激素避孕药与血压变化有关，并且在试图减少对心血管系统的影响时应考虑个人疾病史。
