Tasić Tatjana, Tadić Marijana, Lozić Maja
School of Dental Medicine, University of Belgrade, Belgrade, Serbia.
Clinic for Internal Medicine II, Cardiology Department, University Clinic of Ulm, Ulm, Germany.
Front Cardiovasc Med. 2022 Jun 3;9:905504. doi: 10.3389/fcvm.2022.905504. eCollection 2022.
Hypertension is one of the main causes of morbidity and mortality in the human population. Nevertheless, the intricate network of pathophysiological mechanisms that lead to the development of hypertension in women still awaits to be fully understood. From young age to maturity and senescence, the female body transits through different stages, each of them characterized with specific physiological features and disposition to particular pathological conditions, and that is exactly what makes the understanding of the genesis and adequate treatment of hypertension in women so challenging. Clinical and experimental findings emphasize the role of sex hormones, autonomic nervous system, renin-angiotensin-aldosterone system and arterial stiffness in the development of chronically elevated blood pressure in females. The purpose of this review is to briefly summarize the knowledge of the mechanisms and treatment of hypertension in women.
高血压是人群发病和死亡的主要原因之一。然而,导致女性高血压发生的复杂病理生理机制网络仍有待充分了解。从年轻时到成熟和衰老阶段,女性身体经历不同阶段,每个阶段都有特定的生理特征和对特定病理状况的易感性,而这正是理解女性高血压的发生机制和进行适当治疗极具挑战性的原因。临床和实验结果强调了性激素、自主神经系统、肾素 - 血管紧张素 - 醛固酮系统和动脉僵硬度在女性慢性血压升高发展中的作用。本综述的目的是简要总结女性高血压机制和治疗方面的知识。