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Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new strategy to increase resectability in liver surgery.联合肝脏离断和门静脉结扎的分阶段肝切除术(ALPPS):一种增加肝脏手术可切除性的新策略。
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Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in colorectal liver metastasis: the radiologist's perspective.联合肝脏离断和门静脉结扎的分阶段肝切除术(ALPPS)治疗结直肠癌肝转移:放射科医生的视角。
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Case Report: Robotic ALPPS Procedure for Hepatocellular Carcinoma in the Right Lobe of the Liver.病例报告:机器人辅助的联合肝脏离断和门静脉结扎的二步肝切除术治疗肝右叶肝细胞癌
Front Surg. 2021 Apr 13;8:655683. doi: 10.3389/fsurg.2021.655683. eCollection 2021.
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Associated liver partition and portal vein ligation for staged hepatectomy: a review.联合肝脏分隔和门静脉结扎分期肝切除术:综述
Transl Gastroenterol Hepatol. 2020 Jul 5;5:37. doi: 10.21037/tgh.2019.12.01. eCollection 2020.
4
A better route to ALPPS: minimally invasive vs open ALPPS.更好的 ALPPS 入路:微创与开放 ALPPS。
Surg Endosc. 2020 Jun;34(6):2379-2389. doi: 10.1007/s00464-020-07437-3. Epub 2020 Apr 9.
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ALPPS for hepatocarcinoma under cirrhosis: a feasible alternative to portal vein embolization.肝硬化患者肝癌的联合肝脏分隔和门静脉结扎的二步肝切除术:门静脉栓塞的可行替代方案
Ann Transl Med. 2019 Nov;7(22):691. doi: 10.21037/atm.2019.10.57.

本文引用的文献

1
An updated systematic review of the evolution of ALPPS and evaluation of its advantages and disadvantages in accordance with current evidence.根据当前证据对联合肝脏分割和门静脉结扎的分期肝切除术(ALPPS)的演变及其优缺点进行的最新系统评价。
Medicine (Baltimore). 2016 Jun;95(24):e3941. doi: 10.1097/MD.0000000000003941.
2
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new strategy to increase resectability in liver surgery.联合肝脏离断和门静脉结扎的分阶段肝切除术(ALPPS):一种增加肝脏手术可切除性的新策略。
Int J Surg. 2014;12(5):437-41. doi: 10.1016/j.ijsu.2014.03.009. Epub 2014 Apr 2.
3
Transcatheter arterial chemoembolization followed by immediate radiofrequency ablation for large solitary hepatocellular carcinomas.经导管动脉化疗栓塞后即刻行射频消融治疗大的单发肝细胞癌。
World J Gastroenterol. 2013 Jul 14;19(26):4192-9. doi: 10.3748/wjg.v19.i26.4192.
4
Economic evaluation of da Vinci-assisted robotic surgery: a systematic review.达芬奇机器人手术的经济学评价:系统评价。
Surg Endosc. 2012 Mar;26(3):598-606. doi: 10.1007/s00464-011-1936-2. Epub 2011 Oct 13.
5
Complications of elective liver resections in a center with low mortality: a simple score to predict morbidity.低死亡率中心择期肝切除的并发症:预测发病率的简易评分
Arch Surg. 2011 Nov;146(11):1246-52. doi: 10.1001/archsurg.2011.175. Epub 2011 Jul 18.
6
Preoperative portal vein embolization for major liver resection: a meta-analysis.肝大部切除术前门静脉栓塞术:一项荟萃分析
Ann Surg. 2008 Jan;247(1):49-57. doi: 10.1097/SLA.0b013e31815f6e5b.
7
Place of cryosurgery in the treatment of malignant liver tumors.冷冻手术在恶性肝肿瘤治疗中的地位。
Ann Surg. 1997 Jan;225(1):39-8; discussion 48-50. doi: 10.1097/00000658-199701000-00005.

印度首例机器人辅助一期ALPPS手术:用于结直肠癌肝转移

First Ever Robotic Stage One ALPPS Procedure in India: for Colorectal Liver Metastases.

作者信息

Krishnamurthy Jagadeesh, Naragund Adithya V, Mahadevappa Basant

机构信息

Department of HPB surgery & Liver Transplantation, HCG Hospital, Bengaluru, 560027 India.

出版信息

Indian J Surg. 2018 Jun;80(3):269-271. doi: 10.1007/s12262-017-1713-0. Epub 2017 Dec 21.

DOI:10.1007/s12262-017-1713-0
PMID:29973758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6014955/
Abstract

Twenty five percent of total liver volume (TLV) is considered as the ideal functional liver remnant (FLR) in major liver resections. In patients with macro-vesicular steatosis, early cirrhosis, and post-neoadjuvant chemotherapy (NACT), hepatocellular injury is common. In such instances, up to 40% of FLR may be required. So in cases of marginal FLR, pre-operative portal vein (PV) embolization or two-stage hepatectomy with PV occlusion is used. Both of which take up to 14 weeks between stages and 30% of patients fail to reach the second resection either due to inadequate FLR growth or disease progression. Associated liver partition and portal vein ligation (ALPPS) procedure has become the gold standard for those cases. A 57-year-old male presented with rectosigmoid growth + multiple right liver and segment 4B metastases. Post-NACT MRI showed interval progression of lesions. Preoperative CT (computed tomography) volumetric scan showed a FLR/TLV (future liver remnant/total liver volume) of 22%. Since patient received 10 cycles of NACT, ALPPS procedure was planned ahead of direct liver resection. Robotic ALPPS stage 1 sparing left lateral segment and 4A + anterior resection was done. We transected the parenchyma between the FLR and the diseased part of the liver with concomitant right portal vein ligation done robotically. CT abdomen done on POD7 showed hypertrophied left lateral segment. Second stage was performed on the eighth post-operative day with FLR/TLV increasing to 37%. Robotic ALPPS procedure for stage one is a safe and feasible technique in experienced centers with advanced robotic skills.

摘要

在主要肝脏切除术中,25%的全肝体积(TLV)被视为理想的功能性肝剩余(FLR)。在患有大泡性脂肪变性、早期肝硬化和新辅助化疗(NACT)后的患者中,肝细胞损伤很常见。在这种情况下,可能需要高达40%的FLR。因此,在FLR处于临界状态的病例中,可采用术前门静脉(PV)栓塞或PV闭塞的两阶段肝切除术。这两种方法在两个阶段之间都需要长达14周的时间,并且30%的患者由于FLR生长不足或疾病进展而未能进行第二次切除。联合肝脏分隔和门静脉结扎(ALPPS)手术已成为这些病例的金标准。一名57岁男性患者出现直肠乙状结肠肿物+多发右肝及4B段转移。NACT后MRI显示病变有进展。术前CT(计算机断层扫描)容积扫描显示FLR/TLV(未来肝剩余/全肝体积)为22%。由于患者接受了10个周期的NACT,因此计划在直接肝切除术前进行ALPPS手术。进行了机器人辅助的ALPPS第一阶段手术,保留左外侧段和4A段并进行前切除术。我们通过机器人辅助同时结扎右门静脉,横断了FLR与肝脏病变部分之间的实质。术后第7天进行的腹部CT显示左外侧段肥大。第二阶段手术在术后第8天进行,此时FLR/TLV增加到37%。对于有经验的具备先进机器人技术的中心来说,机器人辅助的ALPPS第一阶段手术是一种安全可行的技术。