孕妇中C组或G组链球菌定植的患病率及临床意义：一项回顾性队列研究
Prevalence and Clinical Significance of (Groups C or G Streptococci) Colonization in Pregnant Women: A Retrospective Cohort Study.
作者信息
Jaalama M, Palomäki O, Vuento R, Jokinen A, Uotila J
机构信息
Department of Obstetrics and Gynecology, Kanta-Häme Central Hospital, Hämeenlinna, Finland.
Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.
出版信息
Infect Dis Obstet Gynecol. 2018 Jun 3;2018:2321046. doi: 10.1155/2018/2321046. eCollection 2018.
OBJECTIVES
Little is known about the significance of Streptococcus G or C colonization in pregnant women. The objective of this study was to assess whether vaginal Streptococcus group G or C colonization detected in late pregnancy increases the infectious morbidity of the mother or newborn.
METHODS
A total of 15,114 rectovaginal cultures taken at 35-37 weeks of pregnancy were analyzed at Tampere University Hospital, Finland, between 2012 and 2014. From this laboratory data, all Streptococcus G or C-positive cultures were included to study maternal and neonatal infectious morbidity after delivery. This study population was compared to women with a positive Streptococcus B culture and to women with a negative culture.
RESULTS
The prevalence of Streptococcus G or C colonization was 2.9%. Significantly more postpartum endometritis was found in this study group. No association was found between colonization and neonatal bacteremia.
CONCLUSIONS
Streptococcus G or C colonization is associated with postpartum endometritis. More research is needed to clarify if antibiotic prophylaxis is reasonable for this group during delivery.
目的
关于孕妇感染G组或C组链球菌的意义，人们所知甚少。本研究的目的是评估妊娠晚期检测到的阴道G组或C组链球菌定植是否会增加母亲或新生儿的感染发病率。
方法
2012年至2014年期间，芬兰坦佩雷大学医院对15114份在妊娠35 - 37周时采集的直肠阴道培养样本进行了分析。从这些实验室数据中，纳入所有G组或C组链球菌阳性培养样本，以研究分娩后母亲和新生儿的感染发病率。将该研究人群与B组链球菌培养阳性的女性以及培养阴性的女性进行比较。
结果
G组或C组链球菌定植的患病率为2.9%。在该研究组中发现产后子宫内膜炎的病例明显更多。未发现定植与新生儿菌血症之间存在关联。
结论
G组或C组链球菌定植与产后子宫内膜炎有关。需要更多研究来阐明分娩期间对该组进行抗生素预防是否合理。
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