The Department of Orthopedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 01008 JPP, Iowa City, IA 52242, USA.
Division of Sports Medicine, Duke University, Durham, North Carolina, USA.
Knee Surg Sports Traumatol Arthrosc. 2019 Jan;27(1):100-104. doi: 10.1007/s00167-018-5034-z. Epub 2018 Jul 4.
The current study compares the Patient Reported Outcomes Information System Physical Function Computer Adaptive Test (PROMIS PF CAT) to traditional knee PRO instruments in a healthy population undergoing surgery for ACL injuries with the following objectives: (1) identify and determine the strength of any correlations between the scores of PROMIS PF CAT and current knee PROs or their subscales that measure physical function; (2) evaluate PROMIS PF CAT's test burden; and (3) determine if PROMIS PF CAT has any floor or ceiling effects in this population.
Patients indicated for ACL surgery completed the Short Form-36 Physical Function (SF-36 PF), Knee Injury and Osteoarthritis Outcome Score (KOOS), Marx Knee Activity Rating Scale (Marx), the EuroQol 5-dimensions Questionnaire (EQ-5D), and PROMIS PF CAT. Correlations between PROs were defined as follows: High (≥ 0.7); high-moderate (0.61-0.69); moderate (0.4-0.6); moderate-weak (0.31-0.39); and weak (≤ 0.3). Floor or ceiling effects were considered significant if 15% or more patients reported the lowest or highest possible total score, respectively.
100 patients participated with a mean age of 26 years (range 11-57). The PROMIS PF CAT demonstrated high correlations with SF-36 PF (r = 0.82, p < 0.01), EQ-5D (r = - 0.70, p < 0.01) KOOS ADL (r = 0.74, p < 0.01), and KOOS Sport (r = 0.70, p < 0.01). There were no ceiling or floor effects for PROMIS PF CAT (0%). The mean number of items completed for the PROMIS PF CAT was 4.2 (median 4; range 4-11).
The PROMIS PF CAT shows a high correlation with commonly employed PROs that also measure physical function with low test burden and without ceiling effects in this relatively young and healthy population.
本研究比较了患者报告结局信息系统（PROMIS）物理功能计算机自适应测试（PF CAT）与传统膝关节 PRO 工具在 ACL 损伤手术患者中的表现，旨在：（1）确定并确定 PROMIS PF CAT 与当前膝关节 PRO 或其测量物理功能的子量表之间的任何相关性及其强度；（2）评估 PROMIS PF CAT 的测试负担；（3）确定 PROMIS PF CAT 在该人群中是否存在地板或天花板效应。
接受 ACL 手术的患者完成了简短形式 36 项健康调查（SF-36 PF）、膝关节损伤和骨关节炎结局评分（KOOS）、马克思膝关节活动评分量表（Marx）、欧洲五维健康量表（EQ-5D）和 PROMIS PF CAT。PRO 之间的相关性定义如下：高（≥0.7）；高-中度（0.61-0.69）；中度（0.4-0.6）；中-弱（0.31-0.39）；弱（≤0.3）。如果有 15%或更多的患者报告了最低或最高的总分，则认为地板或天花板效应显著。
共有 100 名患者参与，平均年龄 26 岁（11-57 岁）。PROMIS PF CAT 与 SF-36 PF（r=0.82，p<0.01）、EQ-5D（r=-0.70，p<0.01）、KOOS ADL（r=0.74，p<0.01）和 KOOS 运动（r=0.70，p<0.01）具有高度相关性。PROMIS PF CAT 无天花板或地板效应（0%）。PROMIS PF CAT 完成的平均项目数为 4.2（中位数 4；范围 4-11）。
在这个相对年轻和健康的人群中，PROMIS PF CAT 与常用的 PRO 具有高度相关性，这些 PRO 也可以测量物理功能，且测试负担低，无天花板效应。
