Cheah Jonathan W, Danilkowicz Richard, Hutyra Carolyn, Lewis Brian, Olson Steve, Poehlein Emily, Green Cynthia L, Mather Richard
Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, U.S.A.
Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, U.S.A.
Arthrosc Sports Med Rehabil. 2022 Jan 5;4(2):e495-e501. doi: 10.1016/j.asmr.2021.11.008. eCollection 2022 Apr.
The purpose of this study was to identify an association between Patient-Reported Outcomes Measurement Information System (PROMIS) sleep scores and other PROMIS domains in patients with femoroacetabular impingement syndrome (FAIS).
Patients were retrospectively identified for FAIS pathology, and PROMIS outcomes were assessed at multiple visits. Individual generalized linear mixed-effects models were fit with PROMIS sleep score as the predictor variable, and each subsequent PROMIS metric as the response variable. Additionally, models were fit using a clinically significant dichotomization of PROMIS sleep score to assess differences in average PROMIS scores between those with disrupted sleep (>55) and those with normal sleep (≤55).
PROMIS scores at baseline differed between those with and without sleep disturbance. Specifically, higher PROMIS sleep scores were associated with higher anxiety, depression, fatigue, pain intensity, and pain interference scores and lower physical function, and social participation.
An association between PROMIS sleep score and other PROMIS outcomes does exist. Sleep disturbance is associated with increased anxiety, depression, fatigue, pain intensity, pain interference and decreased physical function, and social participation when analyzing PROMIS score, as both a continuous and dichotomized variable. Because of the observational design of this study, no causal inference can be made on these results.
Level III, retrospective comparative trial.
本研究旨在确定股骨髋臼撞击综合征(FAIS)患者的患者报告结局测量信息系统(PROMIS)睡眠评分与其他PROMIS领域之间的关联。
对确诊为FAIS病理的患者进行回顾性分析,并在多次就诊时评估PROMIS结局。采用个体广义线性混合效应模型,以PROMIS睡眠评分为预测变量,以每个后续的PROMIS指标为反应变量。此外,使用具有临床意义的PROMIS睡眠评分二分法建立模型,以评估睡眠紊乱(>55)者和睡眠正常(≤55)者之间PROMIS平均评分的差异。
有睡眠障碍和无睡眠障碍者的基线PROMIS评分存在差异。具体而言,较高的PROMIS睡眠评分与较高的焦虑、抑郁、疲劳、疼痛强度和疼痛干扰评分以及较低的身体功能和社会参与度相关。
PROMIS睡眠评分与其他PROMIS结局之间确实存在关联。在分析PROMIS评分时,无论是作为连续变量还是二分变量,睡眠障碍都与焦虑、抑郁、疲劳、疼痛强度、疼痛干扰增加以及身体功能和社会参与度降低相关。由于本研究的观察性设计,无法对这些结果进行因果推断。
III级,回顾性比较试验。