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金属氧化物纳米粒子在电化学生物传感中的应用:综述

Metal oxide nanoparticles in electrochemical sensing and biosensing: a review.

机构信息

School of Chemical Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India.

出版信息

Mikrochim Acta. 2018 Jul 4;185(7):358. doi: 10.1007/s00604-018-2894-3.

DOI:10.1007/s00604-018-2894-3
PMID:29974265
Abstract

This review (with (318) refs) describes progress made in the design and synthesis of morphologically different metal oxide nanoparticles made from iron, manganese, titanium, copper, zinc, zirconium, cobalt, nickel, tungsten, silver, and vanadium. It also covers respective composites and their function and application in the field of electrochemical and photoelectrochemical sensing of chemical and biochemical species. The proper incorporation of chemical functionalities into these nanomaterials warrants effective detection of target molecules including DNA hybridization and sensing of DNA or the formation of antigen/antibody complexes. Significant data are summarized in tables. The review concludes with a discussion or current challenge and future perspectives. Graphical abstract ᅟ.

摘要

这篇综述(引用了 318 篇参考文献)描述了在设计和合成形态不同的金属氧化物纳米粒子方面取得的进展,这些纳米粒子由铁、锰、钛、铜、锌、锆、钴、镍、钨、银和钒制成。它还涵盖了各自的复合材料及其在电化学和光电化学化学和生物化学物种传感领域的功能和应用。将化学官能团适当引入这些纳米材料中,可以保证对目标分子(包括 DNA 杂交)的有效检测,以及对 DNA 或抗原/抗体复合物形成的检测。大量数据以表格形式总结。综述最后讨论了当前的挑战和未来的展望。

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