Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Australian Alzheimer's Research Foundation (Hollywood Private Hospital), Perth, WA, Australia.
Curr Nutr Rep. 2018 Sep;7(3):139-149. doi: 10.1007/s13668-018-0229-y.
The purposes of this review were to examine literature published over the last 5 years and to evaluate the role of nutrition in cognitive function and brain ageing, focussing on the Mediterranean diet (MeDi), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets.
Results suggest that higher adherence to a healthy dietary pattern is associated with preservation of brain structure and function as well as slower cognitive decline, with the MIND diet substantially slowing cognitive decline, over and above the MeDi and DASH diets. Whilst results to-date suggest adherence to a healthy diet, such as the MeDi, DASH, or MIND, is an important modifiable risk factor in the quest to develop strategies aimed at increasing likelihood of healthy brain ageing, further work is required to develop dietary guidelines with the greatest potential benefit for public health; a research topic of increasing importance as the world's population ages.
本综述的目的是研究过去 5 年发表的文献,并评估营养在认知功能和大脑老化中的作用,重点关注地中海饮食(MeDi)、停止高血压的饮食方法(DASH)和地中海- DASH 干预以延缓神经退行性疾病(MIND)饮食。
结果表明,更高的健康饮食模式依从性与脑结构和功能的保持以及认知能力下降的减缓有关,与 MeDi 和 DASH 饮食相比,MIND 饮食显著减缓了认知能力下降。尽管迄今为止的结果表明,遵循健康饮食,如 MeDi、DASH 或 MIND,是一个重要的可改变的风险因素,旨在制定旨在增加健康大脑老化可能性的策略,但需要进一步的工作来制定具有最大公共健康潜在益处的饮食指南;随着世界人口老龄化,这是一个日益重要的研究课题。