Suppr超能文献

老年人的饮食模式与认知。

Dietary patterns and cognition in older persons.

机构信息

Azienda Sanitaria Locale (ASL) di Frosinone, Alzheimer's Disease Clinic Department, Frosinone.

The Univeristy of Campania 'Luigi Vanvitelli', Department of Medical, Surgical, Neurological, Aging and Metabolic Sciences. Caserta, Italy.

出版信息

Curr Opin Clin Nutr Metab Care. 2018 Jan;21(1):10-13. doi: 10.1097/MCO.0000000000000434.

Abstract

PURPOSE OF REVIEW

The current article reviews recently published evidence of the important role that specific dietary patterns may hold on preventing cognitive impairment and dementia over aging.

RECENT FINDINGS

Specific dietary patterns attributed to targeting cardiovascular risk factors may protect against the development of mild cognitive impairment (MCI) and dementia, especially Alzheimer's disease. Numerous epidemiological studies have strongly suggested that multinutrient approaches using the Mediterranean diet (Med diet), dietary approach to systolic hypertension (DASH) and the Mediterranean-DASH diet intervention for neurodegenerative delay (MIND) are associated with a lower risk of cognitive impairment, MCI and Alzheimer's disease in older persons. This multinutrient approach seems to hold better outcomes than single nutrient intervention. There is only one randomized clinical trial (PREDIMED study) showing an improvement in cognitive performance over time in those undergoing a Med diet protocol.

SUMMARY

Nutrition is an essential and modifiable risk factor that plays a role on preventing and/or delaying the onset of dementia. There is sufficient evidence to hypothesize testing neuroprotective dietary patterns on cognition in randomized clinical trials in older persons. Healthy dietary patterns such as the Med diet, DASH and MIND deserve further attention in randomized clinical trials on cognitive performance outcomes.

摘要

目的综述

本文综述了最近发表的关于特定饮食模式在预防认知障碍和衰老相关痴呆中的重要作用的证据。

最近的发现

针对心血管危险因素的特定饮食模式可能有助于预防轻度认知障碍(MCI)和痴呆,尤其是阿尔茨海默病。大量的流行病学研究强烈表明,使用地中海饮食(Med 饮食)、收缩压饮食法(DASH)和针对神经退行性疾病的地中海- DASH 饮食干预(MIND)的多种营养素方法与老年人认知障碍、MCI 和阿尔茨海默病的风险降低相关。这种多种营养素方法似乎比单一营养素干预效果更好。只有一项随机临床试验(PREDIMED 研究)显示,遵循 Med 饮食方案的人群认知表现随时间有所改善。

总结

营养是一个重要且可改变的风险因素,对预防和/或延缓痴呆的发生起着作用。有充分的证据假设在老年人的随机临床试验中测试具有神经保护作用的饮食模式对认知的影响。健康的饮食模式,如 Med 饮食、DASH 和 MIND,值得在认知表现结果的随机临床试验中进一步关注。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验