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基于谷胱甘肽响应的同双硫代缩合杯[4]芳烃的纳米粒子用于选择性细胞内药物递送。

Glutathione-responsive homodithiacalix[4]arene-based nanoparticles for selective intracellular drug delivery.

机构信息

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR, China.

出版信息

Chem Commun (Camb). 2018 Jul 17;54(58):8128-8131. doi: 10.1039/c8cc05031g.

DOI:10.1039/c8cc05031g
PMID:29974903
Abstract

Glutathione-responsive, paclitaxel-loaded nanoparticles based on homodithiacalix[4]arene were successfully developed, exhibiting selective drug release in cancer cells.

摘要

基于同双硫代杯[4]芳烃的谷胱甘肽响应性、载紫杉醇纳米粒子被成功开发，在癌细胞中表现出选择性药物释放。

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