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“巧克力”金纳米颗粒——一锅法合成及其生物相容性

"Chocolate" Gold Nanoparticles-One Pot Synthesis and Biocompatibility.

作者信息

Roy Chowdhury Neelika, Cowin Allison J, Zilm Peter, Vasilev Krasimir

机构信息

School of Engineering, University of South Australia, Mawson Lakes SA 5095, Australia.

Future Industries Institute, University of South Australia, Mawson Lakes SA 5095, Australia.

出版信息

Nanomaterials (Basel). 2018 Jul 5;8(7):496. doi: 10.3390/nano8070496.

DOI:10.3390/nano8070496
PMID:29976891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6071287/
Abstract

The chemical synthesis of nanoparticles can involve and generate toxic materials. Here, we present for the first time, a one pot direct route to synthesize gold nanoparticles (AuNPs) using natural cacao extract as both a reducing and stabilizing agent. The nanoparticles were characterized by UV-visible spectroscopy (UV-VIS), dynamic light scattering (DLS), and transmission electron microscopy (TEM); and have excellent biocompatibility with human primary dermal fibroblasts.

摘要

纳米颗粒的化学合成可能涉及并产生有毒物质。在此,我们首次展示了一种一锅直接法,使用天然可可提取物作为还原剂和稳定剂来合成金纳米颗粒(AuNPs)。通过紫外可见光谱(UV-VIS)、动态光散射(DLS)和透射电子显微镜(TEM)对纳米颗粒进行了表征;并且它们与人类原代表皮成纤维细胞具有出色的生物相容性。

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