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Roux-en-Y胃旁路术后解剖结构中双气囊小肠镜辅助下内镜逆行胰胆管造影术:专家与新手的经验对比

Double balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography in Roux-en-Y gastric bypass anatomy: expert vs. novice experience.

作者信息

Kashani Amir, Abboud Gebran, Lo Simon K, Jamil Laith H

机构信息

Cedars Sinai Medical Center, Division of Gastroenterology, Los Angeles, California, United States.

Conemaugh Memorial Medical Center, Johnstown, Pennsylvania, United States.

出版信息

Endosc Int Open. 2018 Jul;6(7):E885-E891. doi: 10.1055/a-0599-6059. Epub 2018 Jul 4.

Abstract

BACKGROUND AND STUDY AIMS

Double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (DBE-ERCP) in post-Roux-en-Y gastric bypass (RYGB) patients is a technically challenging procedure. We aimed to determine the success rate of DBE-ERCP performed by a novice to the procedure in post-RYGB after training with an expert.

PATIENTS AND METHODS

Medical records for 103 consecutive post-RYGB patients who underwent DBE-ERCP in a tertiary center were retrospectively reviewed. The procedures were performed by Operator A (18 years of high-volume ERCP practice before acquiring DBE skill in 2004), and operator B ( < 2 years' experience in DBE and ERCP). ERCP success rate and time in patients with an intact papilla were compared between Operator A's first and last sets of cases in equal number to the cases performed by Operator B.

RESULTS

A total of 129 DBE-ERCPs were performed (Operator A: 109; Operator B: 20) over an 80-month time span. Among patients with an intact papilla, DBE-ERCP success rates for Operator A's first (87.5 %) and last (92.9 %) 20 cases were similar to that of Operator B (92.9 %) (  = 1.00 for both). Mean of DBE-ERCP time for the last 20 cases of Operator A was (100 minutes; 95 % confidence interval: 81,123) less than that for operator B (176 minutes; 95 % confidence interval: 138,224) (  = 0.01). Overall adverse events rates were 11 % and 5 % for Operators A and B, respectively (  = 0.69): pancreatitis (n = 10), cholangitis (n = 1), and perforation (n = 2); all were mild and treated conservatively.

CONCLUSIONS

Despite the intrinsic technical difficulty, DBE-ERCP can be successfully and safely performed in post-RYGB patients by an endoscopist proficient in both conventional DBE and ERCP. Ideally, this endoscopist should observe several cases of DBE-ERCP performed by an expert to learn the techniques.

摘要

背景与研究目的

在接受过Roux-en-Y胃旁路术(RYGB)的患者中,双气囊小肠镜辅助内镜逆行胰胆管造影术(DBE-ERCP)是一项技术难度较大的操作。我们旨在确定一名初次接触该操作的内镜医师在接受专家培训后,对接受过RYGB手术的患者进行DBE-ERCP的成功率。

患者与方法

回顾性分析了一家三级中心连续103例接受DBE-ERCP的RYGB术后患者的病历。操作由A医生(2004年掌握DBE技术前有18年大量ERCP操作经验)和B医生(DBE和ERCP经验均<2年)进行。将A医生数量与B医生相同的首组和末组完整乳头患者的ERCP成功率及操作时间进行比较。

结果

在80个月的时间跨度内,共进行了129例DBE-ERCP(A医生:109例;B医生:20例)。在完整乳头的患者中,A医生首组20例(87.5%)和末组20例(92.9%)的DBE-ERCP成功率与B医生(92.9%)相似(两者P均=1.00)。A医生末组20例DBE-ERCP的平均操作时间(100分钟;95%置信区间:81,123)短于B医生(176分钟;95%置信区间:138,224)(P=0.01)。A医生和B医生的总体不良事件发生率分别为11%和5%(P=0.69):胰腺炎(n=10)、胆管炎(n=1)和穿孔(n=2);均为轻度,经保守治疗。

结论

尽管存在内在技术难度,但熟练掌握传统DBE和ERCP的内镜医师能够在RYGB术后患者中成功、安全地进行DBE-ERCP。理想情况下,该内镜医师应观摩专家进行的数例DBE-ERCP操作以学习技术。

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