Exposure and Biomonitoring Division, Environmental Health Science and Research Bureau, Health Canada, Ottawa, Canada.
Korean Polar Research Institute, Songdo-dong, Yeonsu-gu, Incheon, Republic of Korea.
Environ Toxicol Chem. 2018 Sep;37(9):2323-2330. doi: 10.1002/etc.4222. Epub 2018 Aug 6.
Polybrominated diphenyl ethers (PBDEs) have been banned or voluntarily withdrawn from commerce worldwide. Declining levels of PBDEs in humans have been reported elsewhere, but not in Korea. We monitored 7 individual PBDE congeners (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, and BDE-183) in 103 human serum samples collected in 2006. The arithmetic mean and median values for the sum of the 7 PBDEs (∑PBDEs) were 7.13 and 6.70 ng/g lipid, respectively. In addition, 6 pooled human serum samples collected in 2006, 2007, 2009, 2011, 2012, and 2013 were analyzed. A decrease in PBDE levels was observed, as reflected by the median value of ∑PBDEs from 5.98 in 2006 to 2.98 ng/g lipid in 2013 as well as in the pooled samples. The levels of individual congeners also decreased but at different declining rates. Based on these results and previously reported data, a definite decline in PBDE levels in the Korean metropolitan population could be observed from 2001 to 2013, providing the first evidence in Korea of the same decline observed elsewhere in the world. Environ Toxicol Chem 2018;37:2323-2330. © 2018 SETAC.
多溴二苯醚 (PBDEs) 已在全球范围内被禁止或自愿退出商业用途。其他地方也有报道称人体内 PBDEs 的水平正在下降，但韩国尚未有相关报道。我们监测了 2006 年采集的 103 个人血清样本中 7 种单体 PBDE 同系物（BDE-28、BDE-47、BDE-99、BDE-100、BDE-153、BDE-154 和 BDE-183）的水平。7 种 PBDE 总和（∑PBDEs）的算术平均值和中位数分别为 7.13 和 6.70ng/g 脂质。此外，还分析了 2006 年、2007 年、2009 年、2011 年、2012 年和 2013 年采集的 6 份混合血清样本。∑PBDEs 的中位数从 2006 年的 5.98ng/g 脂质降至 2013 年的 2.98ng/g 脂质，以及混合样本，表明 PBDE 水平呈下降趋势。个别同系物的水平也有所下降，但下降速度不同。基于这些结果和之前的报告数据，可以观察到韩国大都市人口的 PBDE 水平从 2001 年到 2013 年确实有所下降，这是韩国首次出现与世界其他地区相同的下降趋势。环境毒理化学 2018；37:2323-2330。©2018 SETAC。
