Cole Laura P, Humm Karen
Department of Clinical Science and Services, The Royal Veterinary College, Hatfield, UK.
J Feline Med Surg. 2019 Jun;21(6):481-487. doi: 10.1177/1098612X18785742. Epub 2018 Jul 6.
The objectives of this study were to describe the clinical use and outcome of autologous transfusions in cats with intracavitary haemorrhage.
A retrospective descriptive study was performed. Computerised medical records of a single referral centre were searched for cats receiving an autotransfusion. Medical records were evaluated for underlying disease process, autotransfusion technique, autotransfusion volume, time period over which the autotransfusion was given, packed cell volume (PCV) pre- and post-autotransfusion, percentage rise in PCV, use of other blood products and any complications of the procedure. Survival to discharge and survival at 2 months was documented.
Between July 2012 and March 2018 a total of 12 autotransfusions were performed in eight cats. All patients were diagnosed with haemoperitoneum. Four of the eight cats were diagnosed with abdominal neoplasia, three had postoperative haemorrhage and one had a traumatic haemoperitoneum. Three cats received more than one autotransfusion. Blood was collected using a 23 G butterfly catheter and 20 ml syringe in 7/12 collections, a 23 G needle and 20 ml syringe in 2/12 collections and directly into syringes from the open abdomen at the time of surgery in 3/12 collections. A median volume of 50 ml (range 25-80 ml) was collected and administered, meaning a median volume of 16.5 ml/kg (range 9-26 ml/kg) was administered. The autologous transfusions were given over a median of 3 h (0.25-6 h). Five cats were given another blood product alongside the autotransfusion. Median percentage PCV increase was 5% (range 1-7%). Anticoagulant was used in 5/12 autotransfusions. No clinically relevant adverse effects were reported. Six of the eight cats survived to discharge. Two month survival was 60% (3/5).
Autologous transfusion appears to be a safe and effective technique for stabilising cats with haemoperitoneum. This technique allows rapid and cheap provision of blood and avoids the need for an allogenic blood donor.
本研究的目的是描述自体输血在患有腔内出血的猫中的临床应用及结果。
进行了一项回顾性描述性研究。在一家转诊中心的计算机化医疗记录中搜索接受自体输血的猫。对医疗记录进行评估，内容包括潜在疾病过程、自体输血技术、自体输血量、自体输血的时间段、输血前后的血细胞比容（PCV）、PCV的上升百分比、其他血液制品的使用情况以及该操作的任何并发症。记录出院生存率和2个月生存率。
在2012年7月至2018年3月期间，共对8只猫进行了12次自体输血。所有患者均被诊断为腹腔积血。8只猫中有4只被诊断为腹部肿瘤，3只术后出血，1只创伤性腹腔积血。3只猫接受了不止一次自体输血。12次采血中，7次使用23G蝶形导管和20ml注射器采血，2次使用23G针头和20ml注射器采血，3次在手术时直接从开放的腹腔中采血至注射器。采集并输注的中位数体积为50ml（范围25 - 80ml），这意味着输注的中位数体积为16.5ml/kg（范围9 - 26ml/kg）。自体输血的中位数时间为3小时（0.25 - 6小时）。5只猫在自体输血的同时还接受了其他血液制品。PCV的中位数上升百分比为5%（范围1 - 7%）。12次自体输血中有5次使用了抗凝剂。未报告有临床相关的不良反应。8只猫中有6只存活至出院。2个月生存率为60%（3/5）。
自体输血似乎是一种稳定患有腹腔积血的猫的安全有效技术。该技术能够快速且廉价地提供血液，并且无需异体献血者。
