卡铂和帕博利珠单抗化学免疫疗法使复发性转移性皮脂腺癌实现缓解。
Carboplatin and Pembrolizumab Chemoimmunotherapy Achieves Remission in Recurrent, Metastatic Sebaceous Carcinoma.
作者信息
Kodali Saranya, Tipirneni Eswar, Gibson Pamela C, Cook Deborah, Verschraegen Claire, Lane Katherine A
机构信息
Division of Hematology Oncology, University of Vermont Cancer Center, Burlington, Vermont.
Division of Anatomic Pathology, University of Vermont Medical Center.
出版信息
Ophthalmic Plast Reconstr Surg. 2018 Sep/Oct;34(5):e149-e151. doi: 10.1097/IOP.0000000000001164.
A 72-year-old Caucasian woman who had recurrent sebaceous carcinoma of the right orbit with bilateral cervical lymph node involvement 24 months after orbital exenteration was treated with carboplatin (area under the curve of 5) and pembrolizumab (2 mg/kg) for 6 cycles, followed by maintenance pembrolizumab. She obtained a complete pathological remission and remains free of local, regional, and systemic disease at 15 months.
一名72岁的白种女性，在眼眶内容剜除术后24个月出现右侧眼眶复发性皮脂腺癌并伴有双侧颈部淋巴结受累，接受了卡铂（曲线下面积为5）和帕博利珠单抗（2mg/kg）治疗6个周期，随后接受帕博利珠单抗维持治疗。她获得了完全病理缓解，在15个月时仍无局部、区域和全身疾病。
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