Jang Shin Yi, Seo Su Ra, Moon Ju Ryoung, Cho Eun Jeong, Kim EunKyoung, Chang Sung-A, Song Jinyoung, Huh June, Kang I-Seok, Kim Duk-Kyung, Park Seung Woo
Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul The National Health Insurance Service, Wonju Department of Pediatrics, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul Division of Cardiology, Department of Internal Medicine, Cardiology Clinic, National Cancer Center, Gyeonggi-do, Republic of Korea.
Medicine (Baltimore). 2018 Jul;97(27):e11348. doi: 10.1097/MD.0000000000011348.
The aim of this study was to assess the age-standardized prevalence (prevalence) and age-standardized mortality (mortality) of congenital heart disease (CHD) by sex in Korean adults. Data were collected from the National Health Insurance Service in Korea from 2006 through 2016. The data consisted of main and secondary diagnoses related to CHD. We calculated the prevalence and mortality of CHD in adults with the direct method using the estimated Korean population in 2015 as the reference. The prevalence of CHD in Korean adults increased from 35.8 cases per 100,000 persons in 2006 to 65.6 cases in 2015. In 2015, the prevalence in the 20- to 44-year-old group, 45- to 64-year-old group, and the older than 65 years group was 54.6, 69.6, and 95.1 cases, respectively. Among women, the prevalence was 34.3 and 31.3 cases in men. The mortality of CHD in adults decreased from 3.061 persons per 100,000 persons in 2007 to 0.551 persons in 2015. The 5-year survival rate (SR) for people with CHD was 0.92 (95% confidence interval [CI] 0.91-0.93). The 5-year SR for the 20- to 44- and 45- to 64-year-old groups was more than 0.95; however, the 5-year SR of the older than 65 years group was only 0.73 (95% CI 0.72-0.74). The prevalence of CHD in Korean adults increased and the related mortality decreased during a decade. The 5-year SR of CHD for those over 65 years was lower than that for younger age groups.
本研究旨在评估韩国成年人中按性别划分的先天性心脏病（CHD）的年龄标准化患病率（患病率）和年龄标准化死亡率（死亡率）。数据收集自2006年至2016年韩国国民健康保险服务中心。这些数据包括与CHD相关的主要和次要诊断。我们以2015年韩国估计人口为参考，采用直接法计算成年人中CHD的患病率和死亡率。韩国成年人中CHD的患病率从2006年的每10万人35.8例增加到2015年的65.6例。2015年，20至44岁年龄组、45至64岁年龄组和65岁以上年龄组的患病率分别为54.6例、69.6例和95.1例。女性患病率为34.3例，男性为31.3例。成年人中CHD的死亡率从2007年的每10万人3.061人降至2015年的0.551人。CHD患者的5年生存率（SR）为0.92（95%置信区间[CI]0.91 - 0.93）。20至44岁和45至64岁年龄组的5年SR超过0.95；然而，65岁以上年龄组的5年SR仅为0.73（95%CI 0.72 - 0.74）。在十年间，韩国成年人中CHD的患病率上升而相关死亡率下降。65岁以上人群CHD的5年SR低于年轻年龄组。
