Radda T M, Kuzmits R
Wien Klin Wochenschr. 1985 Nov 8;97(21):801-5.
It is well documented in the literature that patients with active sarcoidosis exhibit elevated serum ACE activity. Since both temporal arteritis and sarcoidosis represent granulomatous inflammatory conditions, this study was undertaken to determine serum ACE activity in patients with temporal arteritis as well as in a control group. The serum ACE levels in patients with temporal arteritis were significantly lower than in the controls. Hence, granulomatous inflammation in temporal arteritis seems to differ radically from the granulomatous inflammation present in sarcoidosis. Serum ACE activity was increasing during cortisone treatment of patients with temporal arteritis, but dropped again as soon as cortisone therapy was discontinued.
文献中有充分记载，患有活动性结节病的患者血清ACE活性升高。由于颞动脉炎和结节病均表现为肉芽肿性炎症，因此开展本研究以测定颞动脉炎患者以及对照组的血清ACE活性。颞动脉炎患者的血清ACE水平显著低于对照组。因此，颞动脉炎中的肉芽肿性炎症似乎与结节病中存在的肉芽肿性炎症有根本差异。在对颞动脉炎患者进行可的松治疗期间，血清ACE活性升高，但一旦停止可的松治疗，血清ACE活性又会再次下降。
