Crouch C F
Vaccine. 1985 Sep;3(3):284-91. doi: 10.1016/s0264-410x(85)90056-8.
Passive immunity against enteric viral infections is dependent upon the continual presence in the gut lumen of a protective level of specific antibodies. This article examines methods currently used to enhance the titre and duration of specific antibody in the mammary secretions of cows and pigs, with particular reference to rotavirus and coronavirus infections. In addition, some of the potential problems to be found in attempting to produce vaccines against these viral infections are outlined.
针对肠道病毒感染的被动免疫依赖于肠道腔内持续存在具有保护水平的特异性抗体。本文探讨了目前用于提高奶牛和猪乳腺分泌物中特异性抗体滴度和持续时间的方法,特别提及轮状病毒和冠状病毒感染。此外,还概述了在尝试生产针对这些病毒感染的疫苗时可能发现的一些潜在问题。