Lee Hsiang-Lin, Peng Cheng-Ming, Huang Cheng-Yu, Wu Shin-Yi, Tsai Ming-Chang, Wang Chi-Chih, Chen Sung-Lang, Lin Chun-Che, Huang Chien-Ning, Sung Wen-Wei
School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
BMJ Open. 2018 Jul 6;8(7):e020618. doi: 10.1136/bmjopen-2017-020618.
The colorectal cancer mortality-to-incidence ratio (MIR) can reflect healthcare disparities. However, a similar association has not yet been established between the MIR of pancreatic cancer and healthcare disparities.
In this study, the incidence and mortality rates of pancreatic cancer were obtained from the GLOBOCAN 2012 database. The WHO rankings and total expenditures on health/gross domestic product (e/GDP) were obtained from a public database. Linear regression was performed to determine correlations between the variables.
57 countries met the inclusion criteria according to the data quality. Developed regions (Europe and the Americas) had high pancreatic cancer incidence and mortality rates. The MIRs were over 0.90 in all regions. No significant correlation was found between MIRs and the WHO rankings, e/GDP or per capita total expenditure on health for analysis in the 57 countries, indicating no association between MIRs and cancer care disparities for pancreatic cancer.
The MIR variations for pancreatic cancer do not correlate with healthcare disparities among countries. Further investigation is necessary to confirm this observation with secondary analysis of databases.
结直肠癌死亡率与发病率之比（MIR）可反映医疗保健差异。然而，胰腺癌的MIR与医疗保健差异之间尚未建立类似的关联。
在本研究中，胰腺癌的发病率和死亡率数据来自全球癌症数据库2012。世界卫生组织排名以及卫生总支出/国内生产总值（e/GDP）数据来自一个公共数据库。进行线性回归以确定变量之间的相关性。
根据数据质量，57个国家符合纳入标准。发达地区（欧洲和美洲）的胰腺癌发病率和死亡率较高。所有地区的MIR均超过0.90。在这57个国家中，MIR与世界卫生组织排名、e/GDP或人均卫生总支出之间未发现显著相关性，这表明胰腺癌的MIR与癌症医疗差异之间没有关联。
胰腺癌的MIR变化与各国之间的医疗保健差异无关。需要进一步调查以通过数据库的二次分析来证实这一观察结果。
