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Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.增强的心肌细胞 NLRP3 炎性小体信号促进心房颤动。
Circulation. 2018 Nov 13;138(20):2227-2242. doi: 10.1161/CIRCULATIONAHA.118.035202.
2
Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.在心力衰竭进展过程中蛋白磷酸酶 1 相互作用组的重排。
Circulation. 2018 Oct 9;138(15):1569-1581. doi: 10.1161/CIRCULATIONAHA.118.034361.
3
Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons.在人类心力衰竭和缺血性心肌病中，活性过高的兰尼碱受体位于偶联点之外。
Cardiovasc Res. 2018 Sep 1;114(11):1512-1524. doi: 10.1093/cvr/cvy088.
4
The role of spatial organization of Ca release sites in the generation of arrhythmogenic diastolic Ca release in myocytes from failing hearts.衰竭心脏心肌细胞中钙释放位点的空间组织在致心律失常舒张期钙释放产生中的作用。
Basic Res Cardiol. 2017 Jul;112(4):44. doi: 10.1007/s00395-017-0633-2. Epub 2017 Jun 13.
5
Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation.蛋白磷酸酶 1（PP1）同工型在人类心力衰竭和心房颤动中的差异调节。
Basic Res Cardiol. 2017 Jul;112(4):43. doi: 10.1007/s00395-017-0635-0. Epub 2017 Jun 9.
6
Calcium Signaling and Cardiac Arrhythmias.钙信号与心律失常
Circ Res. 2017 Jun 9;120(12):1969-1993. doi: 10.1161/CIRCRESAHA.117.310083.
7
Calcium-mediated cellular triggered activity in atrial fibrillation.钙介导的心房颤动细胞触发活动。
J Physiol. 2017 Jun 15;595(12):4001-4008. doi: 10.1113/JP273048. Epub 2017 Mar 22.
8
Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice.巨噬细胞依赖性的 IL-1β 产生导致糖尿病小鼠发生心脏心律失常。
Nat Commun. 2016 Nov 24;7:13344. doi: 10.1038/ncomms13344.
9
Axial tubule junctions control rapid calcium signaling in atria.轴突小管连接调控心房中的快速钙信号传导。
J Clin Invest. 2016 Oct 3;126(10):3999-4015. doi: 10.1172/JCI88241. Epub 2016 Sep 19.
10
Ca(2+) /calmodulin-dependent protein kinase II equally induces sarcoplasmic reticulum Ca(2+) leak in human ischaemic and dilated cardiomyopathy.钙（2+）/钙调蛋白依赖性蛋白激酶 II 同样可诱导人类缺血性和扩张型心肌病肌浆网 Ca（2+）渗漏。
Eur J Heart Fail. 2014 Dec;16(12):1292-300. doi: 10.1002/ejhf.163. Epub 2014 Sep 8.

Pro-arrhythmic RyR2 channels in heart failure: do their localisation and mechanism of activation really matter?

作者信息

Dobrev Dobromir, Fender Anke C, Wehrens Xander H T

机构信息

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Hufelandstrasse 55, Essen, Germany.

Cardiovascular Research Institute and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.

出版信息

Cardiovasc Res. 2018 Sep 1;114(11):1428-1429. doi: 10.1093/cvr/cvy175.

DOI:10.1093/cvr/cvy175
PMID:29982290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6106099/
Abstract
摘要