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婴儿心脏内畸胎瘤:1例新病例报告及文献复习

Intracardiac Teratoma in an Infant: Report of a New Case and Literature Review.

作者信息

Azzakhmam Mustapha, Kessab Amine, Malihy Abderrahmane, Rouas Lamiae, Lamalmi Najat

机构信息

Department of Pathology, Military Hospital of Rabat, Rabat, Morocco.

Department of Pathology, Pediatric Hospital of Rabat, Rabat, Morocco.

出版信息

Case Rep Pathol. 2018 Jun 10;2018:6805234. doi: 10.1155/2018/6805234. eCollection 2018.

Abstract

Primitive intracardiac tumours are rare, especially in childhood, and are often discovered on autopsy. The intracardiac teratoma is the rarest intracardiac tumours of childhood. Herein, we report the case of an 11-month-old infant, which featured recurrent bronchoalveolitis since the age of 3 months, with a thoracic deformation. Physical examination did found discrete respiratory distress signs. Chest radiography showed large mediastinal enlargement. The computed tomography showed a solid cystic-cloisonned mass with fat and central calcification highly suggestive of an intracardiac teratoma. A radical surgical excision was made and the histological examination found a well circumscribed tumour containing elements of the three germ layers confirming the diagnosis of mature well-differentiated teratoma, with no need of immunohistochemical support.

摘要

原发性心脏肿瘤很少见,尤其是在儿童期,且常于尸检时发现。心脏畸胎瘤是儿童期最罕见的心脏肿瘤。在此,我们报告一例11个月大的婴儿病例,该婴儿自3个月大起就反复出现支气管肺泡炎,并伴有胸廓畸形。体格检查发现有明显的呼吸窘迫体征。胸部X线检查显示纵隔明显增宽。计算机断层扫描显示一个实性囊状分隔肿块,伴有脂肪和中央钙化,高度提示为心脏畸胎瘤。进行了根治性手术切除,组织学检查发现一个边界清晰的肿瘤,含有三个胚层的成分,从而确诊为成熟的高分化畸胎瘤,无需免疫组化支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/6015667/e3916b62f352/CRIPA2018-6805234.001.jpg

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