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急性呼吸窘迫综合征:最新进展与综述

Acute Respiratory Distress Syndrome: An Update and Review.

作者信息

Rawal Gautam, Yadav Sankalp, Kumar Raj

机构信息

Attending Consultant, Department of Respiratory Intensive Care, Max Super Specialty Hospital, Saket, New Delhi, India.

General Duty Medical Officer-II, Department of Medicine & TB, Chest Clinic Moti Nagar, North MCD, New Delhi, India.

出版信息

J Transl Int Med. 2018 Jun 26;6(2):74-77. doi: 10.1515/jtim-2016-0012. eCollection 2018 Jun.

DOI:10.1515/jtim-2016-0012
PMID:29984201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6032183/
Abstract

Acute respiratory distress syndrome (ARDS) is a life threatening condition characterized by severe hypoxemia due to pulmonary gas exchange failure and was first recognized in 1960s.Since its first description, it has undergone intensive research in the past few decades to understand its pathogenesis and therapies. Despite this, the recommended therapies to decrease mortality in ARDS remain limited and include low-tidal volume mechanical ventilation, prone ventilation and recently, the ECMO rescue therapy in extreme cases. This review article will summarize the key features of ARDS with a brief overview of the therapeutic options in the management of ARDS.

摘要

急性呼吸窘迫综合征(ARDS)是一种危及生命的病症,其特征为由于肺气体交换衰竭导致的严重低氧血症,于20世纪60年代首次被认识。自首次描述以来,在过去几十年里对其进行了深入研究以了解其发病机制和治疗方法。尽管如此,降低ARDS死亡率的推荐治疗方法仍然有限,包括低潮气量机械通气、俯卧位通气,以及最近在极端情况下的体外膜肺氧合(ECMO)挽救治疗。本文将总结ARDS的关键特征,并简要概述ARDS管理中的治疗选择。

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A randomised controlled trial and cost-effectiveness analysis of high-frequency oscillatory ventilation against conventional artificial ventilation for adults with acute respiratory distress syndrome. The OSCAR (OSCillation in ARDS) study.一项针对急性呼吸窘迫综合征成人患者的高频振荡通气与传统人工通气的随机对照试验及成本效益分析。OSCAR(急性呼吸窘迫综合征中的振荡)研究。
Health Technol Assess. 2015 Mar;19(23):1-177, vii. doi: 10.3310/hta19230.
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