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功能近红外光谱在自闭症研究中的应用前景:我们了解什么,我们的前进方向在哪里?

The promise of functional near-infrared spectroscopy in autism research: What do we know and where do we go?

机构信息

a School of Psychiatry, University of New South Wales , Sydney , Australia.

b Cooperative Research Centre for Living with Autism (Autism CRC) , Brisbane , Queensland , Australia.

出版信息

Soc Neurosci. 2019 Oct;14(5):505-518. doi: 10.1080/17470919.2018.1497701. Epub 2018 Jul 21.

Abstract

Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technique that has been gaining increasing interest as a method to investigate the brain function of individuals on the autism spectrum. It is a non-invasive, portable and relatively motion-tolerant method of measuring haemodynamic activity in the brain. fNIRS can be particularly effective for quantifying brain function in challenging clinical populations. In light of this, there is a growing body of fNIRS literature focusing on individuals on the autism spectrum. The aim of this review is to evaluate and summarise key studies from the literature and discuss their implications for the field. Potential limitations of the fNIRS approach and resolution of these issues based on emerging fNIRS research are also discussed.

摘要

功能近红外光谱(fNIRS)是一种神经影像学技术,作为一种研究自闭症谱系个体大脑功能的方法,它越来越受到关注。它是一种非侵入性、便携式且相对抗运动的测量大脑血液动力学活动的方法。fNIRS 在量化具有挑战性的临床人群的大脑功能方面特别有效。有鉴于此,越来越多的 fNIRS 文献集中在自闭症谱系个体上。本综述的目的是评估和总结文献中的关键研究,并讨论其对该领域的意义。还讨论了 fNIRS 方法的潜在局限性以及基于新兴 fNIRS 研究解决这些问题的方法。

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