Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Dev Cogn Neurosci. 2019 Apr;36:100635. doi: 10.1016/j.dcn.2019.100635. Epub 2019 Mar 8.
Mobile electroencephalography (mobile EEG) represents a next-generation neuroscientific technology - to study real-time brain activity - that is relatively inexpensive, non-invasive and portable. Mobile EEG leverages state-of-the-art hardware alongside established advantages of traditional EEG and recent advances in signal processing. In this review, we propose that mobile EEG could open unprecedented possibilities for studying neurodevelopmental disorders. We first present a brief overview of recent developments in mobile EEG technologies, emphasising the proliferation of studies in several neuroscientific domains. As these developments have yet to be exploited by neurodevelopmentalists, we then identify three research opportunities: 1) increase in the ease and flexibility of brain data acquisition in neurodevelopmental populations; 2) integration into powerful developmentally-informative research designs; 3) development of innovative non-stationary EEG-based paradigms. Critically, we address key challenges that should be considered to fully realise the potential of mobile EEG for neurodevelopmental research and for understanding developmental psychopathology more broadly, and suggest future research directions.
移动脑电图(mobile EEG)代表了一种下一代神经科学技术 - 用于实时研究大脑活动 - 它相对便宜、非侵入性且便携。移动 EEG 利用最先进的硬件以及传统 EEG 的优势和信号处理的最新进展。在这篇综述中,我们提出移动 EEG 可能为研究神经发育障碍开辟前所未有的可能性。我们首先简要介绍移动 EEG 技术的最新发展,强调在几个神经科学领域研究的普及。由于神经发育学家尚未利用这些发展,我们随后确定了三个研究机会:1)增加神经发育人群中大脑数据采集的简便性和灵活性;2)整合到强大的具有发展意义的研究设计中;3)开发基于创新非稳态 EEG 的范式。至关重要的是,我们解决了应该考虑的关键挑战,以充分实现移动 EEG 在神经发育研究中的潜力,并更广泛地理解发展性精神病理学,并提出了未来的研究方向。