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Mitochondrial function in thoracic aortic aneurysms.

作者信息

Yu Emma, Foote Kirsty, Bennett Martin

机构信息

Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Box 110 ACCI, Cambridge, UK.

出版信息

Cardiovasc Res. 2018 Nov 1;114(13):1696-1698. doi: 10.1093/cvr/cvy180.

DOI:10.1093/cvr/cvy180
PMID:29985972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6198732/
Abstract
摘要

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2
Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice.恢复线粒体 DNA 拷贝数可维持线粒体功能并延缓小鼠血管衰老。
Aging Cell. 2018 Aug;17(4):e12773. doi: 10.1111/acel.12773. Epub 2018 May 9.
3
Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics.
利用综合生物信息学分析探索与胸主动脉瘤相关的免疫细胞中线粒体功能的潜在改变。
Bioengineering (Basel). 2025 Feb 17;12(2):197. doi: 10.3390/bioengineering12020197.
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Oxidative Stress and the Pathogenesis of Aortic Aneurysms.氧化应激与主动脉瘤的发病机制
Biomedicines. 2023 Dec 19;12(1):3. doi: 10.3390/biomedicines12010003.
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Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.Wnt16 通过激活 Taz（Wwtr1）促进雄性 LDLR-/- 小鼠血管平滑肌收缩表型和功能。
Endocrinology. 2023 Dec 23;165(2). doi: 10.1210/endocr/bqad192.
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Molecular Pathogenesis and the Possible Role of Mitochondrial Heteroplasmy in Thoracic Aortic Aneurysm.分子发病机制及线粒体异质性在胸主动脉瘤中的可能作用
Life (Basel). 2021 Dec 13;11(12):1395. doi: 10.3390/life11121395.
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Oxidative stress in genetically triggered thoracic aortic aneurysm: role in pathogenesis and therapeutic opportunities.遗传性胸主动脉瘤中的氧化应激：在发病机制和治疗机会中的作用。
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