Rafiei Reza, Rafiei Abdollah, Rahdar Mahmoud, Keikhaie Bijan
Department of Parasitology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Parasitology, Faculty of Medicine, Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Parasite Epidemiol Control. 2016 Aug 5;1(3):229-232. doi: 10.1016/j.parepi.2016.08.001. eCollection 2016 Sep.
Strongyloidiasis is a life-threatening parasitic infection, especially in immunosuppressed patients, with death often occurring within several days. The disease has a worldwide distribution and is endemic in tropical and subtropical regions. Therefore, this study was conducted to investigate seroepidemiology of infection amongst immunocompromised patients in Southwest Iran. This cross-sectional study was conducted amongst a population of immunocompromised patients who were referred to health care or hospital referral centres in Ahvaz, Southwest Iran. Serum samples were tested by an enzyme immunoassay for -IgG antibody. Anti- antibody was detected in 39 of 270 immunocommpromised cases, yielding a prevalence of 14.4%. No significant differences were indicated in terms of gender, age, or type of immunocompromised disorder with - antibody levels. In conclusion, our results demonstrated high seroepidemiology of infection with this parasite in the region. Therefore, it appears immunocompromised patients should be tested for this infection using sensitive tests. However, current research underscores that strongyloidosis must not be neglected, and further assessments in high risk population are warranted.
类圆线虫病是一种危及生命的寄生虫感染,尤其在免疫功能低下的患者中,患者常在数天内死亡。该病在全球范围内均有分布,在热带和亚热带地区为地方性流行病。因此,本研究旨在调查伊朗西南部免疫功能低下患者中的类圆线虫感染血清流行病学。这项横断面研究在伊朗西南部阿瓦士的医疗保健机构或医院转诊中心的免疫功能低下患者群体中进行。血清样本通过酶免疫测定法检测抗类圆线虫IgG抗体。在270例免疫功能低下病例中,有39例检测到抗类圆线虫抗体,患病率为14.4%。在性别、年龄或免疫功能低下疾病类型方面,抗类圆线虫抗体水平无显著差异。总之,我们的结果表明该地区这种寄生虫感染的血清流行病学水平较高。因此,似乎应对免疫功能低下患者使用敏感检测方法进行该感染的检测。然而,当前研究强调类圆线虫病绝不能被忽视,对高危人群进行进一步评估是必要的。