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卵巢静脉血栓形成的新型管理:一例报告

Novel management of ovarian vein thrombosis: A case report.

作者信息

Naoum Joseph, Mohsen Amani, Daher Jihad, Eid Toufic

机构信息

Chief Division of Vascular and Endovascular Surgery, Lebanese American University (LAU) and Lebanese American University Medical Center Rizk Hospital (LAUMCRH), Beirut, Lebanon.

Obstetrics & Gynecology consultant at Médecins Sans Frontières (MSF), Beirut, Lebanon.

出版信息

Saudi Pharm J. 2018 Jul;26(5):608-610. doi: 10.1016/j.jsps.2018.03.003. Epub 2018 Mar 7.

DOI:10.1016/j.jsps.2018.03.003
PMID:29988955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6035329/
Abstract

Ovarian vein thrombosis (OVT) is a rare serious diagnosis especially if extending to inferior vein cava (IVC). We present a case of 36-year- old female who was diagnosed with right OVT reaching the inferior vein cava following a supra-cervical hysterectomy that was performed in the postpartum period due to excessive bleeding from uterine fibroids. Using the new generation anti-coagulant "rivaroxaban" for six months followed by maintenance regimen of aspirin and sulodexide, complete resolution of the clot was noticed without any adverse event while using this regimen. This is the first OVT case which is completely treated with rivaroxaban without any adjunct invasive modality.

摘要

卵巢静脉血栓形成(OVT)是一种罕见的严重诊断,尤其是当血栓延伸至下腔静脉(IVC)时。我们报告一例36岁女性,因子宫肌瘤产后出血行宫颈上子宫切除术后被诊断为右侧OVT并延伸至下腔静脉。使用新一代抗凝剂“利伐沙班”六个月,随后采用阿司匹林和舒洛地昔维持治疗方案,在此治疗方案期间,血栓完全溶解,未出现任何不良事件。这是首例仅使用利伐沙班完全治愈且未采用任何辅助侵入性治疗方式的OVT病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4db4/6035329/3890a8e319b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4db4/6035329/a5c4b9ea69bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4db4/6035329/3890a8e319b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4db4/6035329/a5c4b9ea69bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4db4/6035329/3890a8e319b7/gr2.jpg

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本文引用的文献

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Thromb Res. 2016 Oct;146:84-88. doi: 10.1016/j.thromres.2016.09.001. Epub 2016 Sep 5.
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Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report.抗栓治疗 VTE 疾病:CHEST 指南和专家小组报告。
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Postpartum ovarian vein thrombosis manifesting as acute appendicitis: a case report.产后卵巢静脉血栓形成表现为急性阑尾炎:一例报告
J Med Case Rep. 2021 Oct 25;15(1):521. doi: 10.1186/s13256-021-03102-y.
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Ovarian Vein Thrombosis Can Be a Complication of Hysteroscopy.卵巢静脉血栓形成可能是宫腔镜检查的一种并发症。
Cureus. 2021 Jul 5;13(7):e16196. doi: 10.7759/cureus.16196. eCollection 2021 Jul.
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Ovarian vein thrombosis in the postnatal period.产后卵巢静脉血栓形成。
BMJ Case Rep. 2021 Jun 25;14(6):e243872. doi: 10.1136/bcr-2021-243872.
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Direct oral anticoagulants for unusual-site venous thromboembolism.用于非常见部位静脉血栓栓塞的直接口服抗凝剂。
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