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孟加拉国的 H9N2 流感病毒:在鸡和新世界鹌鹑中的传播。

H9N2 influenza viruses from Bangladesh: Transmission in chicken and New World quail.

机构信息

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee.

Department of Zoology, Jahangirnagar University, Dhaka, Bangladesh.

出版信息

Influenza Other Respir Viruses. 2018 Nov;12(6):814-817. doi: 10.1111/irv.12589. Epub 2018 Sep 8.

DOI:10.1111/irv.12589
PMID:29989679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6185884/
Abstract

The H9N2 influenza viruses that have become established in Bangladeshi live poultry markets possess five gene segments of the highly pathogenic H7N3 avian influenza virus. We assessed the replication, transmission, and disease potential of three H9N2 viruses in chickens and New World quail. Each virus replicated to high titers and transmitted by the airborne route to contacts in both species. Infected chickens showed no disease signs, and the viruses differed in their disease potential in New World quail. New World quail were more susceptible than chickens to H9N2 viruses and shed virus after airborne transmission for 10 days. Consequently, New World quail are a potential threat in the maintenance and spread of influenza virus in live poultry markets.

摘要

在孟加拉国活禽市场中立足的 H9N2 流感病毒拥有高致病性 H7N3 禽流感病毒的五个基因片段。我们评估了三种 H9N2 病毒在鸡和新世界鹌鹑中的复制、传播和疾病潜力。每种病毒都能复制到很高的滴度,并通过空气传播途径传播给两种物种的接触者。感染鸡没有出现疾病迹象,而病毒在新世界鹌鹑中的疾病潜力不同。新世界鹌鹑比鸡更容易感染 H9N2 病毒,并且在空气传播后 10 天内仍能排出病毒。因此,新世界鹌鹑是活禽市场中流感病毒维持和传播的潜在威胁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95dd/6185884/80ca6c7963d6/IRV-12-814-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95dd/6185884/80ca6c7963d6/IRV-12-814-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95dd/6185884/80ca6c7963d6/IRV-12-814-g001.jpg

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