Huang C H, Liang H C, Jia F L
Intervirology. 1985;24(3):147-53. doi: 10.1159/000149634.
M14 virus, isolated from Culex tritaeniorhynchus mosquitoes collected in a Beijing suburb, was identified as a noncytopathogenic orbi-like virus. It was found to interfere with the growth of Japanese encephalitis (JE) virus, a mosquito-borne virus which infects humans, pigs, and horses in much of Asia, including China. JE virus is transmitted by C. tritaeniorhynchus mosquitoes and causes encephalitis in humans and horses and abortion in pigs. Because it had potential as an interfering agent for the biological control of JE, the M14 virus was characterized and its interfering effect was studied in mice and in C. tritaeniorhynchus mosquitoes.
从北京郊区采集的三带喙库蚊中分离出的M14病毒，被鉴定为一种无细胞病变的类环状病毒。研究发现，它能干扰乙型脑炎（JE）病毒的生长。JE病毒是一种通过蚊子传播的病毒，在包括中国在内的亚洲大部分地区感染人类、猪和马。JE病毒由三带喙库蚊传播，可导致人类和马患脑炎，猪流产。由于M14病毒具有作为JE生物防治干扰剂的潜力，因此对其进行了特性鉴定，并在小鼠和三带喙库蚊中研究了其干扰作用。
