Son Youn-Jung, Kwon Bo Eun
Red Cross College of Nursing, Chung-Ang University, Seoul, Korea.
Seoul Women's College of Nursing, Seoul, Korea.
Int Neurourol J. 2018 Jun;22(2):77-82. doi: 10.5213/inj.1836120.060. Epub 2018 Jun 30.
The prevalence of Heart failure (HF) is expected to increase worldwide with the aging population trend. The numerous symptoms of and repeated hospitalizations for HF negatively affect the patient's quality of life and increase the patient's economic burden. Up to 50% of patients with HF suffer from urinary incontinence (UI) and an overactive bladder (OAB). However, there are limited data about the relationship between UI, OAB, and HF. The association between HF and urinary symptoms may be directly attributable to worsening HF pathophysiology. A comprehensive literature review was conducted for all publications between January 2000 and November 2017 using the PubMed, Embase, and Cochrane databases. HF represents a major and growing public health problem, with an increased risk of UI and an OAB as comorbidities. Possible effects of HF on urinary problems may be mediated by the prescription of medications for symptomatic relief. Although diuretics are typically used to relieve congestion, and angiotensin-converting enzyme inhibitors and angiotensin receptor blockers improve survival, these classes of drugs have been suggested to worsen urinary symptoms in the presence of HF. Further research is required to understand the impact of UI and an OAB on the HF illness trajectory.
随着全球人口老龄化趋势,心力衰竭(HF)的患病率预计将会上升。HF的众多症状以及反复住院对患者的生活质量产生负面影响,并增加患者的经济负担。高达50%的HF患者患有尿失禁(UI)和膀胱过度活动症(OAB)。然而,关于UI、OAB与HF之间关系的数据有限。HF与泌尿系统症状之间的关联可能直接归因于HF病理生理学的恶化。使用PubMed、Embase和Cochrane数据库,对2000年1月至2017年11月期间的所有出版物进行了全面的文献综述。HF是一个日益严重的主要公共卫生问题,UI和OAB作为合并症的风险增加。HF对泌尿系统问题的可能影响可能是通过使用缓解症状的药物来介导的。尽管利尿剂通常用于缓解充血,血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂可提高生存率,但有人认为这些药物类别在存在HF时会加重泌尿系统症状。需要进一步研究以了解UI和OAB对HF疾病进程的影响。