ICAP at Columbia University, Mailman School of Public Health, New York, Department of Epidemiology, Columbia University, New York.
HIV Center for Clinical & Behavioral Studies, Division of Gender, Sexuality and Health, New York State Psychiatric Institute and Columbia University, Department of Psychiatry, New York.
Int J Tuberc Lung Dis. 2018 Aug 1;22(8):858-862. doi: 10.5588/ijtld.17.0809.
Shorter-duration regimens for preventing drug-susceptible tuberculosis (TB) have been shown to be safe and efficacious in children, and may improve acceptability, adherence, and treatment completion. While these regimens have been used in children in low TB burden countries, they are not yet widely used in high TB burden countries.
Five health facilities in one district in Lesotho, a high TB burden country.
Assess the preventive treatment preferences of care givers of child TB contacts.
Qualitative data were collected using in-depth interviews with 12 care givers whose children completed preventive treatment, and analyzed using grounded theory.
Care givers were interested in being involved in the children's treatment decisions. Pill burden, treatment duration and related frequency of dosing were identified as important factors that influenced preventive treatment preferences among care givers.
Understanding care giver preferences and involving them in treatment decisions may facilitate efforts to implement successful preventive treatment for TB among children in high TB burden countries.
较短疗程的方案已被证明可安全有效地预防耐多药结核病（TB），且可能提高可接受性、依从性和治疗完成率。虽然这些方案已在低结核病负担国家的儿童中使用，但尚未在高结核病负担国家广泛使用。
莱索托一个区的五家卫生机构，该国结核病负担高。
评估儿童结核接触者照料者对预防治疗的偏好。
对 12 名完成预防治疗的儿童照料者进行深入访谈，收集定性数据，并使用扎根理论进行分析。
照料者有兴趣参与儿童的治疗决策。药物负担、治疗持续时间和相关给药频率被确定为影响照料者预防治疗偏好的重要因素。
了解照料者的偏好并让他们参与治疗决策，可能有助于在高结核病负担国家为儿童实施成功的结核病预防治疗。
