Costa Flávia Martins, Canella Clarissa, Vieira Filipa Gomes, Vianna Evandro Miguelote, Meohas Walter, Marchiori Edson
MD, PhD, Clínica de Diagnóstico Por Imagem (CDPI), Rio de Janeiro, RJ, Brazil.
MD, PhD, Clínica de Diagnóstico Por Imagem (CDPI), Rio de Janeiro, RJ, and Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil.
Radiol Bras. 2018 May-Jun;51(3):156-161. doi: 10.1590/0100-3984.2017.0037.
The purpose of this study was to determine whether chemical-shift magnetic resonance imaging (MRI) could be useful in the diagnosis of osteoid osteoma when clinical and radiological tumor features are inconclusive.
This retrospective study included 17 patients who underwent chemical-shift MRI for the evaluation of osteoid osteoma. For all patients, two musculoskeletal radiologists independently recorded signal intensities on in-phase and out-of-phase images in the nidus of the tumor, in abnormal-intensity bone marrow surrounding the lesion, and in normal-appearing bone marrow. For each region, relative signal intensity ratios were calculated by dividing out-of-phase by in-phase values. Relative ratios > 1 were considered indicative of neoplastic lesions. Statistical analysis was carried out to analyze the sample. Inter-observer and intra-observer agreement for each imaging method were assessed using intraclass correlation coefficients according to the Fleiss method and a value > 0.65 was considered to indicate substantial agreement.
The mean relative signal intensity ratios were 1.2 (range, 0.9-1.4) for the nidus and 0.35 (range, 0.11-0.66) for the surrounding tissue; these values differed significantly from the relative signal-intensity ratios for normal-appearing bone marrow ( < 0.05).
Chemical-shift MRI is useful for the diagnosis and evaluation of osteoid osteoma.
本研究旨在确定当临床和放射学肿瘤特征不明确时，化学位移磁共振成像（MRI）是否有助于骨样骨瘤的诊断。
这项回顾性研究纳入了17例接受化学位移MRI检查以评估骨样骨瘤的患者。对于所有患者，两名肌肉骨骼放射科医生独立记录肿瘤巢、病变周围异常信号强度骨髓以及外观正常骨髓在同相位和反相位图像上的信号强度。对于每个区域，通过将反相位值除以同相位值来计算相对信号强度比。相对比值>1被认为提示肿瘤性病变。对样本进行统计分析。根据Fleiss方法使用组内相关系数评估每种成像方法的观察者间和观察者内一致性，值>0.65被认为表示高度一致性。
肿瘤巢的平均相对信号强度比为1.2（范围0.9 - 1.4），周围组织为0.35（范围0.11 - 0.66）；这些值与外观正常骨髓的相对信号强度比有显著差异（<0.05）。
化学位移MRI对骨样骨瘤的诊断和评估有用。
