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磁共振骨髓 Dixon 技术

The Dixon technique for MRI of the bone marrow.

机构信息

Department of Medical Imaging, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.

Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.

出版信息

Skeletal Radiol. 2019 Dec;48(12):1861-1874. doi: 10.1007/s00256-019-03271-4. Epub 2019 Jul 15.

DOI:10.1007/s00256-019-03271-4
PMID:31309243
Abstract

Dixon sequences are established as a reliable MRI technique that can be used for problem-solving in the assessment of bone marrow lesions. Unlike other fat suppression methods, Dixon techniques rely on the difference in resonance frequency between fat and water and in a single acquisition, fat only, water only, in-phase and out-of-phase images are acquired. This gives Dixon techniques the unique ability to quantify the amount of fat within a bone lesion, allowing discrimination between marrow-infiltrating and non-marrow-infiltrating lesions such as focal nodular marrow hyperplasia. Dixon can be used with gradient echo and spin echo techniques, both two-dimensional and three-dimensional imaging. Another advantage is its rapid acquisition time, especially when using traditional two-point Dixon gradient echo sequences. Overall, Dixon is a robust fat suppression method that can also be used with intravenous contrast agents. After reviewing the available literature, we would like to advocate the implementation of additional Dixon sequences as a problem-solving tool during the assessment of bone marrow pathology.

摘要

狄克逊序列是一种可靠的 MRI 技术,可用于解决骨髓病变评估中的问题。与其他脂肪抑制方法不同,狄克逊技术依赖于脂肪和水之间的共振频率差异,并且在单个采集过程中,仅采集脂肪、水、同相和反相图像。这使得狄克逊技术具有定量骨病变内脂肪量的独特能力,从而能够区分骨髓浸润性和非骨髓浸润性病变,例如局灶性结节状骨髓增生。狄克逊可与梯度回波和自旋回波技术一起使用,包括二维和三维成像。另一个优点是其快速采集时间,尤其是在使用传统的两点狄克逊梯度回波序列时。总的来说,狄克逊是一种强大的脂肪抑制方法,也可以与静脉内造影剂一起使用。在回顾了现有文献后,我们主张在评估骨髓病理学时将附加的狄克逊序列作为一种解决问题的工具。

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The Dixon technique for MRI of the bone marrow.磁共振骨髓 Dixon 技术
Skeletal Radiol. 2019 Dec;48(12):1861-1874. doi: 10.1007/s00256-019-03271-4. Epub 2019 Jul 15.
2
Improved contrast for myeloma focal lesions with T2-weighted Dixon images compared to T1-weighted images.与 T1 加权图像相比,T2 加权 Dixon 图像可提高骨髓瘤局灶性病变的对比度。
Diagn Interv Imaging. 2019 Sep;100(9):513-519. doi: 10.1016/j.diii.2019.05.001. Epub 2019 May 23.
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Contrast-Enhanced Dixon Fat-Water Separation Imaging of the Spine: Added Value of Fat, In-Phase and Opposed-Phase Imaging in Marrow Lesion Detection.脊柱对比增强狄克逊脂肪-水分离成像:脂肪、同相位和反相位成像在骨髓病变检测中的附加价值
J Comput Assist Tomogr. 2016 Nov/Dec;40(6):985-990. doi: 10.1097/RCT.0000000000000453.
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Fat suppression at three-dimensional T1-weighted MR imaging of the hands: Dixon method versus CHESS technique.双手三维 T1 加权磁共振成像的脂肪抑制: Dixon 法与 CHESS 技术。
Diagn Interv Imaging. 2018 Jan;99(1):23-28. doi: 10.1016/j.diii.2017.09.004. Epub 2017 Oct 18.
5
Fast three-point dixon MR imaging using low-resolution images for phase correction: a comparison with chemical shift selective fat suppression for pediatric musculoskeletal imaging.使用低分辨率图像进行相位校正的快速三点狄克逊磁共振成像:与化学位移选择性脂肪抑制在儿科肌肉骨骼成像中的比较
AJR Am J Roentgenol. 2001 Nov;177(5):1019-23. doi: 10.2214/ajr.177.5.1771019.
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Clinical experience with two-point mDixon turbo spin echo as an alternative to conventional turbo spin echo for magnetic resonance imaging of the pediatric knee.两点 mDixon 涡轮自旋回波在儿科膝关节磁共振成像中替代传统涡轮自旋回波的临床经验。
Pediatr Radiol. 2019 May;49(6):791-800. doi: 10.1007/s00247-019-04349-w. Epub 2019 Feb 6.
7
T1-weighted fat-suppressed imaging of the pelvis with a dual-echo Dixon technique: initial clinical experience.盆腔双回波 Dixon 技术 T1 加权抑脂成像:初步临床经验。
Radiology. 2011 Feb;258(2):583-9. doi: 10.1148/radiol.10100912. Epub 2010 Nov 15.
8
Comparison of the artifacts caused by metallic implants in breast MRI using dual-echo dixon versus conventional fat-suppression techniques.比较双回波 Dixon 与传统脂肪抑制技术在乳腺 MRI 中金属植入物伪影的差异。
AJR Am J Roentgenol. 2014 Sep;203(3):W307-14. doi: 10.2214/AJR.13.10791.
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Fast three-dimensional dual echo dixon technique improves fat suppression in breast MRI.快速三维双回波 Dixon 技术可改善乳腺 MRI 的脂肪抑制效果。
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10
Development and evaluation of TWIST Dixon for dynamic contrast-enhanced (DCE) MRI with improved acquisition efficiency and fat suppression.TWIST Dixon 技术的开发与评估:用于动态对比增强磁共振成像(DCE-MRI)的高效采集和脂肪抑制技术。
J Magn Reson Imaging. 2012 Aug;36(2):483-91. doi: 10.1002/jmri.23663. Epub 2012 Apr 27.

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Eur Radiol Exp. 2025 Sep 10;9(1):89. doi: 10.1186/s41747-025-00615-9.
2
A three-material model for dual-layer detector spectral computed tomography measurements of marrow adipose tissue and bone mineral density.一种用于双层探测器光谱计算机断层扫描测量骨髓脂肪组织和骨矿物质密度的三材料模型。
JBMR Plus. 2025 Apr 16;9(6):ziaf066. doi: 10.1093/jbmrpl/ziaf066. eCollection 2025 Jun.
3
Bone marrow magnetic resonance imaging (MRI): morphological and functional features from reconversion to infiltration.

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Quantitative evaluation of T2* relaxation times for the differentiation of acute benign and malignant vertebral body fractures.定量评估 T2* 弛豫时间在鉴别急性良恶性椎体骨折中的作用。
Eur J Radiol. 2018 Nov;108:59-65. doi: 10.1016/j.ejrad.2018.09.021. Epub 2018 Sep 18.
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Prediction of Abnormal Bone Density and Osteoporosis From Lumbar Spine MR Using Modified Dixon Quant in 257 Subjects With Quantitative Computed Tomography as Reference.利用改良 Dixon Quant 对 257 例以定量 CT 为参考的受试者腰椎 MR 进行异常骨密度和骨质疏松预测。
J Magn Reson Imaging. 2019 Feb;49(2):390-399. doi: 10.1002/jmri.26233. Epub 2018 Nov 3.
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骨髓磁共振成像(MRI):从再转化到浸润的形态学和功能特征
Quant Imaging Med Surg. 2024 Nov 1;14(11):7969-7982. doi: 10.21037/qims-23-1678. Epub 2024 Apr 8.
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[MR Imaging Features of Pediatric Bone Marrow].[小儿骨髓的磁共振成像特征]
J Korean Soc Radiol. 2024 May;85(3):505-519. doi: 10.3348/jksr.2024.0039. Epub 2024 May 29.
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Whole-orbit-based multiparametric assessment of disease activity of thyroid eye disease on Dixon MRI.基于全眼眶的多参数评估狄克逊 MRI 甲状腺眼病的疾病活动度。
Int Ophthalmol. 2024 May 3;44(1):213. doi: 10.1007/s10792-024-03138-1.
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Patient centered radiology: investigating 3 Tesla whole body MRI acceptance in cancer patients.以患者为中心的放射学:研究癌症患者对 3T 全身 MRI 的接受度。
Radiol Med. 2023 Aug;128(8):960-969. doi: 10.1007/s11547-023-01665-y. Epub 2023 Jul 3.
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Dual-energy CT virtual non-calcium: an accurate method for detection of knee osteoarthritis-related edema-like marrow signal intensity.双能CT虚拟去钙技术:一种检测膝关节骨关节炎相关水肿样骨髓信号强度的准确方法。
Insights Imaging. 2023 Apr 30;14(1):74. doi: 10.1186/s13244-023-01407-8.
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Characterizing the Bone Marrow Environment in Advanced-Stage Myelofibrosis during Ruxolitinib Treatment Using PET/CT and MRI: A Pilot Study.应用 PET/CT 和 MRI 技术在鲁索利替尼治疗晚期骨髓纤维化患者中对骨髓微环境进行特征分析:一项初步研究。
Tomography. 2023 Feb 21;9(2):459-474. doi: 10.3390/tomography9020038.
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Dixon T2 imaging of vertebral bone edema: reliability and comparison with short tau inversion recovery.Dixon T2 成像技术在椎体骨水肿中的应用:可靠性及与短 tau 反转恢复序列的比较。
Acta Radiol. 2024 Mar;65(3):273-283. doi: 10.1177/02841851221146130. Epub 2022 Dec 22.
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World J Clin Cases. 2022 Sep 6;10(25):8906-8921. doi: 10.12998/wjcc.v10.i25.8906.
Whole-Body Magnetic Resonance Imaging in Oncology: Uses and Indications.
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Magn Reson Imaging Clin N Am. 2018 Nov;26(4):495-507. doi: 10.1016/j.mric.2018.06.003.
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Acta Radiol. 2019 Apr;60(4):509-515. doi: 10.1177/0284185118786073. Epub 2018 Aug 21.
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Radiol Bras. 2018 May-Jun;51(3):156-161. doi: 10.1590/0100-3984.2017.0037.
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Whole-Body MRI with Diffusion-Weighted Imaging in Bone Metastases: A Narrative Review.全身磁共振成像联合扩散加权成像在骨转移瘤中的应用:一篇叙述性综述
Diagnostics (Basel). 2018 Jul 9;8(3):45. doi: 10.3390/diagnostics8030045.
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Skeletal Radiol. 2018 Dec;47(12):1661-1671. doi: 10.1007/s00256-018-2999-0. Epub 2018 Jun 23.
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