生物合成核壳结构铜@铂纳米颗粒的抗菌活性

Antimicrobial activity of the biogenically synthesized core-shell Cu@Pt nanoparticles.

作者信息

Dobrucka Renata, Dlugaszewska Jolanta

机构信息

Department of Industrial Products Quality and Ecology, Faculty of Commodity Science, Poznan University of Economics, al. Niepodległości 10, 61-875 Poznan, Poland.

Department of Genetics and Pharmaceutical Microbiology, Poznan University of Medical Sciences, 10 Fredry Street, 61-701 Poznan, Poland.

出版信息

Saudi Pharm J. 2018 Jul;26(5):643-650. doi: 10.1016/j.jsps.2018.02.028. Epub 2018 Feb 15.

The interest in the biological synthesis of mono metal nanoparticles has been visible for years. As more attention is also given to the biological methods of synthesizing bimetallic nanoparticles, this work used the extract in order to obtain bimetallic core-shell Cu@Pt nanoparticles. The formed core-shell Cu@Pt nanoparticles were characterized by Ultraviolet-Visible (UV-vis), Fourier Transform-Infrared (FT-IR), Scanning electron microscopy (SEM), Transmission Electron Microscopy (TEM) and Atomic Force Microscopy (AFM) measurements. The obtained core-shell Cu@Pt nanoparticles were analysed in terms of their antibacterial activity. It was discovered that the synthesized nanoparticles exhibited maximum activity against gram-negative bacteria ATCC 25922, ATCC 25923, and NCTC 6749. The core-shell Cu@Pt nanoparticles also exhibited activity against the yeast ATCC 10231 and dermatophytes ATCC 9533.

多年来，人们对单金属纳米颗粒的生物合成一直很感兴趣。随着对双金属纳米颗粒生物合成方法的关注度不断提高，这项工作使用提取物来获得核壳结构的Cu@Pt双金属纳米颗粒。通过紫外可见光谱（UV-vis）、傅里叶变换红外光谱（FT-IR）、扫描电子显微镜（SEM）、透射电子显微镜（TEM）和原子力显微镜（AFM）测量对形成的核壳结构Cu@Pt纳米颗粒进行了表征。对获得的核壳结构Cu@Pt纳米颗粒的抗菌活性进行了分析。发现合成的纳米颗粒对革兰氏阴性菌ATCC 25922、ATCC 25923和NCTC 6749表现出最大活性。核壳结构Cu@Pt纳米颗粒对酵母ATCC 10231和皮肤癣菌ATCC 9533也表现出活性。