Dhanalekshmi K I, Meena K S
PG & Research Department of Chemistry, Queen Mary's College, Chennai 600 004, Tamil Nadu, India.
PG & Research Department of Chemistry, Queen Mary's College, Chennai 600 004, Tamil Nadu, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jul 15;128:887-90. doi: 10.1016/j.saa.2014.02.063. Epub 2014 Mar 7.
Core-shell type Ag@TiO2 nanoparticles were prepared by one pot simultaneous reduction of AgNO3 and hydrolysis of Ti (IV) isopropoxide and Ag@SiO2 core-shell nanoparticles were prepared by Stober's method. They were characterized by absorption, XRD, and HR-TEM techniques. XRD patterns show the presence of anatase form of TiO2 and amorphous form of SiO2 and the noble metal (Ag). High resolution transmission electron microscopy measurements revealed that their size is below 50 nm. The antibacterial properties of Ag@TiO2 and Ag@SiO2 core-shell nanoparticles against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were examined by the agar diffusion method. As a result E. coli and S. aureus were shown to be substantially inhibited by Ag@TiO2 and Ag@SiO2 core-shell nanoparticles. These results demonstrated that TiO2 and SiO2 supported on the surface of Ag NPs without aggregation was proved to have enhanced antibacterial activity.
通过一锅法同时还原硝酸银和异丙醇钛水解制备了核壳型Ag@TiO₂纳米颗粒，并采用施托伯法制备了Ag@SiO₂核壳纳米颗粒。通过吸收、XRD和高分辨透射电子显微镜技术对它们进行了表征。XRD图谱显示存在TiO₂的锐钛矿形式、SiO₂的无定形形式以及贵金属（Ag）。高分辨率透射电子显微镜测量表明它们的尺寸低于50 nm。采用琼脂扩散法研究了Ag@TiO₂和Ag@SiO₂核壳纳米颗粒对大肠杆菌（E. coli）和金黄色葡萄球菌（S. aureus）的抗菌性能。结果表明，Ag@TiO₂和Ag@SiO₂核壳纳米颗粒对大肠杆菌和金黄色葡萄球菌有显著抑制作用。这些结果表明，负载在Ag NPs表面的TiO₂和SiO₂没有聚集，被证明具有增强的抗菌活性。
