Lukina G I, Krikheli N I, Ivannikova A V, Gioeva Y A
Moscow State Medical and Dental University, Moscow, Russia.
Stomatologiia (Mosk). 2018;97(3):23-29. doi: 10.17116/stomat201897323.
The aim of the study was to compare dental and periodontal status, oral hygiene, salivation rate, functional parameters of saliva and oral microbiota composition in patients with gastroesophageal reflux disease (GERD) with acidic and subacidic refluctant. The study comprised 69 participants divided in 3 groups: 22 healthy volunteers (controls) and 2 main groups: 25 GERD patients with acidic (group 2) and 22 patients with subacidic refluctant (group 3). Poor dental and periodontal condition was revealed in group 3 patients probably because of aggressive intestinal content reflux in the oral cavity resulting in higher PMA an saliva pH values, Escherichia coli species in oral microbiota and low buffer capacity of saliva. The results show that GERD may be suspected due to oral manifestations thus promoting it's prompt treatment.
该研究的目的是比较胃食管反流病(GERD)患者中酸性和亚酸性反流患者的牙齿和牙周状况、口腔卫生、唾液分泌率、唾液功能参数以及口腔微生物群组成。该研究包括69名参与者,分为3组:22名健康志愿者(对照组)和2个主要组:25名酸性GERD患者(第2组)和22名亚酸性反流患者(第3组)。第3组患者显示出较差的牙齿和牙周状况,这可能是由于肠道内容物大量反流至口腔,导致唾液中PMA和pH值升高、口腔微生物群中存在大肠杆菌以及唾液缓冲能力较低。结果表明,GERD可能由于口腔表现而被怀疑,从而促进其及时治疗。