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胃食管反流病患者与非胃食管反流病患者唾液 pH 值、缓冲能力和流量的比较研究。

Comparative Study of Salivary pH, Buffer Capacity, and Flow in Patients with and without Gastroesophageal Reflux Disease.

机构信息

Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh, Marinescu Str., 540142 Targu Mures, Romania.

Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh, Marinescu Str., 540142 Targu Mures, Romania.

出版信息

Int J Environ Res Public Health. 2021 Dec 25;19(1):201. doi: 10.3390/ijerph19010201.

Abstract

The oral cavity has specific and individualized characteristics, with pH, saliva flow, buffer capacity, temperature, and microorganisms content influencing oral health. Currently, the prevalence of gastroesophageal reflux disease (GERD) is constantly increasing. The objective of this study was to evaluate and compare the saliva quantity at 5 min, salivary pH, and salivary buffer capacity in patients with and without GERD, necessary for establishing the correct dental treatment plan. A Saliva-Check Buffer (GC) kit was used for the determination of salivary variables. The total number of 80 patients included in the study were divided into a study group and a control group, each containing 40 patients. Saliva quantity at 5 min was lower in patients suffering from GERD. The salivary pH of these patients turned to acid values compared to the salivary pH of controls, where the values were within the normal range. In patients with GERD, the determined salivary buffer capacity was low or very low. The use of the Saliva-Check Buffer (GC) kit is a simple, easy, non-invasive and patient-accepted method, which can also be used in the dentist's office to assess the saliva buffer capacity and pH, variables that are important for establishing a correct dental treatment plan.

摘要

口腔具有特定的个体特征,其 pH 值、唾液流量、缓冲能力、温度和微生物含量都会影响口腔健康。目前,胃食管反流病(GERD)的患病率不断增加。本研究旨在评估和比较 GERD 患者和非 GERD 患者的唾液量在 5 分钟时、唾液 pH 值和唾液缓冲能力,这是制定正确的牙科治疗计划所必需的。使用 Saliva-Check Buffer(GC)试剂盒来确定唾液变量。研究共纳入 80 例患者,分为研究组和对照组,每组各 40 例。患有 GERD 的患者在 5 分钟时的唾液量较低。与对照组的唾液 pH 值相比,这些患者的唾液 pH 值呈酸性,而对照组的唾液 pH 值在正常范围内。在 GERD 患者中,确定的唾液缓冲能力较低或非常低。使用 Saliva-Check Buffer(GC)试剂盒是一种简单、易用、非侵入性且患者易于接受的方法,也可以在牙医诊室中使用,以评估唾液缓冲能力和 pH 值,这些变量对于制定正确的牙科治疗计划很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a0c/8750732/1ef10c45e3e5/ijerph-19-00201-g001.jpg

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