IEEE J Biomed Health Inform. 2019 May;23(3):1066-1074. doi: 10.1109/JBHI.2018.2845303. Epub 2018 Jun 7.
Sleep apnea, a serious sleep disorder affecting a large population, causes disruptions in breathing during sleep. In this paper, an automatic apnea detection scheme is proposed using single lead electroencephalography (EEG) signal to discriminate apnea patients and healthy subjects as well as to deal with the difficult task of classifying apnea and nonapnea events of an apnea patient. A unique multiband subframe based feature extraction scheme is developed to capture the feature variation pattern within a frame of EEG data, which is shown to exhibit significantly different characteristics in apnea and nonapnea frames. Such within-frame feature variation can be better represented by some statistical measures and characteristic probability density functions. It is found that use of Rician model parameters along with some statistical measures can offer very robust feature qualities in terms of standard performance criteria, such as Bhattacharyya distance and geometric separability index. For the purpose of classification, proposed features are used in K Nearest Neighbor classifier. From extensive experimentations and analysis on three different publicly available databases it is found that the proposed method offers superior classification performance in terms of sensitivity, specificity, and accuracy.
睡眠呼吸暂停是一种影响大量人群的严重睡眠障碍,它会导致睡眠期间呼吸中断。本文提出了一种使用单导联脑电图(EEG)信号的自动睡眠呼吸暂停检测方案,用于区分睡眠呼吸暂停患者和健康受试者,并处理对睡眠呼吸暂停患者的呼吸暂停和非呼吸暂停事件进行分类的困难任务。开发了一种独特的多波段子帧基于特征提取方案,以捕获 EEG 数据帧内的特征变化模式,结果表明,在呼吸暂停和非呼吸暂停帧中,这种帧内特征变化具有明显不同的特征。一些统计度量和特征概率密度函数可以更好地表示这种帧内特征变化。研究发现,使用瑞利模型参数以及一些统计度量可以在标准性能标准(如 Bhattacharyya 距离和几何可分离性指数)方面提供非常稳健的特征质量。为了进行分类,所提出的特征用于 K 最近邻分类器。通过在三个不同的公开可用数据库上进行广泛的实验和分析,发现该方法在灵敏度、特异性和准确性方面提供了卓越的分类性能。