Kim Jae Guk, Lee Juncheol, Choi Hyun Young, Kim Wonhee, Kim Jihoon, Moon Shinje, Shin Hyungoo, Ahn Chiwon, Cho Youngsuk, Shin Dong Geum, Lee Yoonje
Department of Emergency Medicine, Hallym University College of Medicine.
Department of Emergency Medicine, Graduate School of Medicine, Kangwon National University, Chuncheon.
Medicine (Baltimore). 2020 Nov 6;99(45):e23095. doi: 10.1097/MD.0000000000023095.
The variation in the outcome of traumatic out-of-hospital cardiac arrest (TOHCA) patients according to the mechanism of injury has been relatively unexplored. Therefore, this study aimed to determine whether the mechanism of injury is associated with survival to hospital discharge and good neurological outcome at hospital discharge in TOHCA.The study population comprised cases of TOHCA drawn from the national Out-of-hospital cardiac arrest registry (2012-2016). Traumatic causes were categorized into 6 groups: traffic accident, fall, collision, stab injury, and gunshot injury. Data were retrospectively extracted from emergency medical service and Korean Centers for Disease Control and Prevention records. Multivariate logistic regression analysis was used to identify factors associated with survival to discharge and good neurological outcome.The final analysis included a total of 8546 eligible TOHCA patients (traffic accident 5300, fall 2419, collision 572, stab injury 247, and gunshot injury 8). The overall survival rate was 18.4% (traffic accident 18.0%, fall 16.4%, collision 32.0%, stab injury 14.2%, and gunshot injury 12.5%). Good neurological outcome was achieved in 0.8% of all patients (traffic accident 0.8%, fall 0.8%, collision 1.2%, stab injury 0.8%, and gunshot injury 0.0%). In the multivariate analysis, injury mechanisms showed no significant difference in neurological outcomes, and only collision had a significant odds ratio for survival to discharge (odds ratio: 2.440; 95% confidence interval: 1.795-3.317) compared to the traffic accident group.In this study, the mechanism of injury was not associated with neurological outcome in TOHCA patients. Collision might be the only mechanism of injury to result in better survival to discharge than traffic accident.
根据损伤机制,院外创伤性心脏骤停(TOHCA)患者的预后差异相对未得到充分研究。因此,本研究旨在确定损伤机制是否与TOHCA患者出院存活及出院时良好神经功能结局相关。研究人群包括从国家院外心脏骤停登记处(2012 - 2016年)抽取的TOHCA病例。创伤原因分为6组:交通事故、跌倒、碰撞、刺伤和枪伤。数据从紧急医疗服务和韩国疾病控制与预防中心记录中回顾性提取。采用多因素逻辑回归分析确定与出院存活及良好神经功能结局相关的因素。最终分析共纳入8546例符合条件的TOHCA患者(交通事故5300例、跌倒2419例、碰撞572例、刺伤247例、枪伤8例)。总体存活率为18.4%(交通事故18.0%、跌倒16.4%、碰撞32.0%、刺伤14.2%、枪伤12.5%)。所有患者中0.8%实现了良好神经功能结局(交通事故0.8%、跌倒0.8%、碰撞1.2%、刺伤0.8%、枪伤0.0%)。在多因素分析中,损伤机制在神经功能结局方面无显著差异,与交通事故组相比,仅碰撞在出院存活方面具有显著优势比(优势比:2.440;95%置信区间:1.795 - 3.317)。在本研究中,损伤机制与TOHCA患者的神经功能结局无关。碰撞可能是唯一一种导致出院存活率高于交通事故的损伤机制。