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创伤性和非创伤性院外心脏骤停后成功复苏的院前决定因素。

Prehospital determinants of successful resuscitation after traumatic and non-traumatic out-of-hospital cardiac arrest.

机构信息

Research and Clinical Innovation, East Anglian Air Ambulance, Norwich, UK.

Academic Department of Military Emergency Medicine, Royal Centre for Defence Medicine (Research and Clinical Innovation), Birmingham, UK.

出版信息

Emerg Med J. 2019 Jun;36(6):333-339. doi: 10.1136/emermed-2018-208165. Epub 2019 Apr 19.

Abstract

BACKGROUND

Out-of-hospital cardiac arrest (OHCA) is prevalent in the UK. Reported survival is lower than in countries with comparable healthcare systems; a better understanding of outcome determinants may identify areas for improvement.

METHODS

An analysis of 9109 OHCA attended in East of England between 1 January 2015 and 31 July 2017. Univariate descriptives and multivariable analysis were used to understand the determinants of survival for non-traumatic cardiac arrest (NTCA) and traumatic cardiac arrest (TCA). Two Utstein outcome variables were used: survival to hospital admission and hospital discharge.

RESULTS

The incidence of OHCA was 55.1 per 100 000 population/year. The overall survival to hospital admission was 27.6% (95% CI 26.7% to 28.6%) and the overall survival to discharge was 7.9% (95% CI 7.3% to 8.5%). Survival to hospital admission and survival to hospital discharge were both greater in the NTCA group compared with the TCA group: 27.9% vs 19.3% p=0.001, and 8.0% vs 3.8% p=0.012 respectively.Determinants of NTCA and TCA survival were different, and varied according to the outcome examined. In NTCA, bystander cardiopulmonary resuscitation (CPR) was associated with survival at discharge but not at admission, and the likelihood of bystander CPR was dependent on geographical socioeconomic status. An air ambulance was associated with increased survival to both hospital admission and discharge in NTCA, but only with survival to admission in TCA.

CONCLUSION

NTCA and TCA are clinically distinct entities with different predictors for outcome-future OHCA reports should aim to separate arrest aetiologies. Determinants of survival to hospital admission and discharge differ in a way that likely reflects the determinants of neurological injury. Bystander CPR public engagement may be best focused in more deprived areas.

摘要

背景

院外心脏骤停(OHCA)在英国很常见。报告的存活率低于具有类似医疗保健系统的国家;更好地了解结局决定因素可能会确定需要改进的领域。

方法

对 2015 年 1 月 1 日至 2017 年 7 月 31 日期间在英格兰东部接受治疗的 9109 例 OHCA 进行了分析。使用单变量描述性分析和多变量分析来了解非创伤性心脏骤停(NTCA)和创伤性心脏骤停(TCA)的生存决定因素。使用了两个 Utstein 结局变量:住院入院生存率和出院生存率。

结果

OHCA 的发病率为每 100000 人口/年 55.1 例。总体入院生存率为 27.6%(95%CI 26.7%至 28.6%),总体出院生存率为 7.9%(95%CI 7.3%至 8.5%)。与 TCA 组相比,NTCA 组的入院生存率和出院生存率均更高:27.9%比 19.3%,p=0.001,8.0%比 3.8%,p=0.012。NTCA 和 TCA 的生存决定因素不同,且根据所检查的结局而有所不同。在 NTCA 中,旁观者心肺复苏术(CPR)与出院生存率相关,但与入院生存率无关,旁观者 CPR 的可能性取决于地理位置的社会经济地位。空中救护与 NTCA 的入院和出院生存率增加相关,但仅与 TCA 的入院生存率相关。

结论

NTCA 和 TCA 是临床上不同的实体,其结局预测因素也不同——未来的 OHCA 报告应旨在区分骤停病因。入院和出院生存率的决定因素存在差异,这可能反映了神经损伤的决定因素。旁观者 CPR 的公众参与可能最好集中在较贫困地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cb5/6582713/a514f985c34f/emermed-2018-208165f01.jpg

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