Winterfield R W, Reed W M, Thacker H L
Poult Sci. 1985 Nov;64(11):2076-80. doi: 10.3382/ps.0642076.
Avian pox virus was isolated from cutaneous pox lesions removed from turkey breeders that had been vaccinated three times with a commercial fowl pox vaccine. In three cross-immunization experiments with turkeys and two with chickens, the turkey pox isolate, designated NC5271, proved immunologically different from fowl, pigeon, and quail pox viruses. Significant protection against NC5271 virus infection and inducement of pox lesions was only attained when the homologous isolate was used as a vaccine. The potential need in the field for such a vaccine was discussed.
从已接种三次商业禽痘疫苗的种火鸡身上切除的皮肤痘疹病变中分离出禽痘病毒。在对火鸡进行的三次交叉免疫实验以及对鸡进行的两次交叉免疫实验中，名为NC5271的火鸡痘分离株在免疫方面被证明与禽痘、鸽痘和鹌鹑痘病毒不同。只有当使用同源分离株作为疫苗时，才能获得针对NC5271病毒感染的显著保护并诱导痘疹病变。文中讨论了该领域对这种疫苗的潜在需求。
